|
| Status |
Public on May 17, 2023 |
| Title |
Pharmacological Inhibition of TAK1 Prevents and Induces Regression of fibrosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To evaluate the effects of TAK1 inhibition on TGF-beta regulated fibrosis using a novel small molecule inhibitor of TAK1.
|
| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for foreskin fibroblast and treated with TGFb1 and TAK1 inhibitor (Control, TGFb1 and TAK1 inhibitor (HS-276)+TGFb1).
|
| |
|
| Contributor(s) |
Bale S, Verma P, Bhattacharya S, Varga J |
| Citation(s) |
37306632 |
| |
| Submission date |
May 12, 2023 |
| Last update date |
Sep 14, 2023 |
| Contact name |
Bioinformatics Core |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Michigan
|
| Street address |
BRCF Bioinformatics Core, 2800 Plymouth Rd
|
| City |
Ann Arbor |
| State/province |
Mi |
| ZIP/Postal code |
48109-2800 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA971977 |
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