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| Status |
Public on Dec 25, 2023 |
| Title |
Effect of PD-1 knockout on Mtb infection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the effect pf PD-1 knockout during Mtb infection, wild type mice and PD-1 knockout mice were infected with Mtb and BMDC were isolated for the transcriptome analysis.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for BMDC of wild type and PD-1 knockout mice infected/uninfected with Mtb.
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| Contributor(s) |
Yang B, Cao X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Dec 02, 2022 |
| Last update date |
Dec 25, 2023 |
| Contact name |
Bing Yang |
| E-mail(s) |
[email protected]
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| Organization name |
Huazhong Agricultural University
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| Department |
College of Vetirinary Medicine
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| Lab |
Gang Cao's Lab
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| Street address |
No.1 Shizishan Street, Hongshan District
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| City |
Wuhan |
| State/province |
Hubei |
| ZIP/Postal code |
430000 |
| Country |
China |
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| Platforms (1) |
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| Samples (12)
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| GSM6779289 |
bone marrow derived dendritic cells, uninfection, 1 |
| GSM6779290 |
bone marrow derived dendritic cells, uninfection, 2 |
| GSM6779291 |
bone marrow derived dendritic cells, uninfection, 3 |
| GSM6779292 |
bone marrow derived dendritic cells, Mtb infected, 1 |
| GSM6779293 |
bone marrow derived dendritic cells, Mtb infected, 2 |
| GSM6779294 |
bone marrow derived dendritic cells, Mtb infected, 3 |
| GSM6779295 |
PD-1 KO bone marrow derived dendritic cells, uninfection, 1 |
| GSM6779296 |
PD-1 KO bone marrow derived dendritic cells, uninfection, 2 |
| GSM6779297 |
PD-1 KO bone marrow derived dendritic cells, uninfection, 3 |
| GSM6779298 |
PD-1 KO bone marrow derived dendritic cells, Mtb infected, 1 |
| GSM6779299 |
PD-1 KO bone marrow derived dendritic cells, Mtb infected, 2 |
| GSM6779300 |
PD-1 KO bone marrow derived dendritic cells, Mtb infected, 3 |
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| Relations |
| BioProject |
PRJNA907818 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE219261_normalized_counts.tsv.gz |
1.4 Mb |
(ftp)(http) |
TSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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