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| Status |
Public on Mar 02, 2023 |
| Title |
Electroacupuncture Alleviates Perioperative Hypothalamus-Pituitary-Adrenal Axis Dysfunction via CircRNA-miRNA-mRNA Networks [circRNA] |
| Organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Electroacupuncture (EA) has long been used to treat surgery-induced hypothalamic-pituitary-adrenal (HPA) axis dysfunction. However, its target gene expression profiles in the brain remain unclear. Thus, the aim of the present study was to clarify the potential targets of EA based on RNA sequencing techniques (RNA-seq). Rats were randomly divided into normal control, hepatectomy surgery (HT), HT+EA, and HT+sham EA groups followed by RNA-seq of two representative nuclei in the hypothalamus and amygdala.
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| Overall design |
mRNA, miRNA, circRNA profiling analysis of mouse hypothalamus and amygdala with modeling of normal control, hepatectomy surgery (HT), HT+EA, and HT+sham EA
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| Contributor(s) |
Hu W, Xu T, Jiang N, Chen M |
| Citation(s) |
36760604 |
| |
| Submission date |
Sep 27, 2022 |
| Last update date |
Mar 02, 2023 |
| Contact name |
Wei Hu |
| E-mail(s) |
[email protected]
|
| Phone |
+17717429024
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| Organization name |
Fudan university
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| Street address |
Dongan Road 130
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| City |
Shanghai |
| ZIP/Postal code |
200030 |
| Country |
China |
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| Platforms (1) |
| GPL18694 |
Illumina HiSeq 2500 (Rattus norvegicus) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE214279 |
Electroacupuncture Alleviates Perioperative Hypothalamus-Pituitary-Adrenal Axis Dysfunction via CircRNA-miRNA-mRNA Networks |
|
| Relations |
| BioProject |
PRJNA884697 |
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