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Series GSE205309 Query DataSets for GSE205309
Status Public on Jun 14, 2022
Title ChIP-sequencing of PRMT1 proficient and deficient microglia
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary ChIP_sequencing analysis defined a novel role for the PRMT1 in microglia during normal and 0.2% cuprizone diet 5weeks
We then performed ChIP analysis using data obtained from ChIP-seq of microglia at two time points
 
Overall design Microglia ChIP profiles of 4-6 weeks-old wild-type (PRMT1Ifl/fl) and microglia specific knockout (PRMT1fl/fl; cx3r1cre-ert2) mice during normal and 0.2% cuprizone diet 5 weeks

Samples 1 to 10 (GSM6210097-GSM6210106) represent anti_H3K27Ac ChIP; while Samples 11 to 19 (GSM6210107-GSM6210115) are the inputs; they consisted in 1% aliquots of the samples taken post-sonication, but before IP.
 
Contributor(s) Lee J, Richard S, Gosselin D
Citation(s) 35705491
Submission date Jun 01, 2022
Last update date Jul 14, 2022
Contact name Stephane Richard
E-mail(s) [email protected]
Phone 5143408260
Organization name Lady Davis Institute- Jewish General Hospital
Street address Lady Davis Institute, 3755 Cot
City Montreal
State/province Quebec
ZIP/Postal code H3T 1E2
Country Canada
 
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (19)
GSM6210097 PRMT1Ifl/fl microglia normal diet_rep1
GSM6210098 PRMT1Ifl/fl microglia normal diet_rep2
GSM6210099 PRMT1fl/fl; cx3r1cre-ert2 microglia normal diet_rep1
Relations
BioProject PRJNA844360

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE205309_ChIP_seq_differential.xlsx 3.1 Mb (ftp)(http) XLSX
GSE205309_Differential_ChIP_PRMT1.xlsx 26.8 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record
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