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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 21, 2022 |
| Title |
RNA-Seq of mice omenta after intraperitoneal (IP) or systemic delivery (IV) of tumor-specific T cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We sought to investigate if and how the alternative delivery methods could differentially impact the gene expression profiles in the tumor microenvironment.
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| Overall design |
Mice were injected intraperitoneally with B16-OVA cell line which homes to the omentum. 6 days post tumor challenge, we treated mice with tumor-specific T cells electroporated with IL-12-coding mRNA either IP or IV. 18h after treatment we isolated omenta and extracted RNA to further continue with sequencing.
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| Contributor(s) |
Di Trani CA, Gomar C, Cabrera JR, Arrizabalaga L, Gomariz JG, Marchese FP |
| Citation(s) |
36531687 |
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| Submission date |
Feb 28, 2022 |
| Last update date |
Dec 21, 2022 |
| Contact name |
Jose Gonzalez |
| E-mail(s) |
[email protected]
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| Organization name |
FIMA
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| Street address |
C/PIO XII s/n
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| City |
Pamplona |
| State/province |
Navarra |
| ZIP/Postal code |
31008 |
| Country |
Spain |
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| Platforms (1) |
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| Samples (9)
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| GSM5923736 |
Tumor-bearing mouse injected with PBS, mouse 1 |
| GSM5923737 |
Tumor-bearing mouse injected with PBS, mouse 2 |
| GSM5923738 |
Tumor-bearing mouse injected with PBS, mouse 3 |
| GSM5923739 |
Tumor-bearing mouse injected IP, mouse 2 |
| GSM5923740 |
Tumor-bearing mouse injected IP, mouse 3 |
| GSM5923741 |
Tumor-bearing mouse injected IP, mouse 4 |
| GSM5923742 |
Tumor-bearing mouse injected IV, mouse 1 |
| GSM5923743 |
Tumor-bearing mouse injected IV, mouse 2 |
| GSM5923744 |
Tumor-bearing mouse injected IV, mouse 4 |
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| Relations |
| BioProject |
PRJNA811177 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE197612_Normalized_log2cpm_counts.txt.gz |
1.2 Mb |
(ftp)(http) |
TXT |
| GSE197612_Raw_counts_data.txt.gz |
629.6 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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