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| Status |
Public on Jun 15, 2021 |
| Title |
Expression data of HNSCC cell lines grown without and with patient-matched CAFs in 2D |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Cancer associated fibroblasts (CAFs) are the major cellular component of the tumor microenvironment and they have been shown to stimulate tumor growth, epithelial-to-mesenchymal transition (EMT), invasion and radio-resistance.
We used microarrays to investigate the influence of CAFs on the gene expression profile of HNSCC cells in 2D co-cultures
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| Overall design |
HNSCC cells (LK0824, LK0858, LK0923, LK0942, LK0949) grown as CAF co-culture in 2D were selected for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Wiechec E, Kankainen M, Roberg K |
| Citation(s) |
34283070 |
| |
| Submission date |
Jun 14, 2021 |
| Last update date |
Aug 11, 2021 |
| Contact name |
Emilia Wiechec |
| E-mail(s) |
[email protected]
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| Organization name |
Linköping University
|
| Department |
Biomedical and Clinical Sciences
|
| Street address |
Sandbäcksgatan 7
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| City |
Linköping |
| ZIP/Postal code |
58183 |
| Country |
Sweden |
| |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (10)
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| GSM5381030 |
LK0824 cell line grown without CAF in 2D |
| GSM5381031 |
LK0858 cell line grown without CAF in 2D |
| GSM5381032 |
LK0923 cell line grown without CAF in 2D |
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| Relations |
| BioProject |
PRJNA737482 |
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