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| Status |
Public on Nov 06, 2020 |
| Title |
Next generation sequencing of the transcriptome of NPC cell line C666_1 under various drug treatments. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The NPC cell line C666_1 is known to be infected with Epstein Barr virus (EBV), and to have high expression of SSTR2A. The cell line was treated with PENN221 (an SSTR2A targeted drug conjugate) , Belinostat (a histone deacetylase inhibitor), DMSO (negative control) or left untreated (negative control). Both PENN221 and Belinstat resulted in increased cell death of the cell line. Treated samples were sequenced at 24h and 72h post treatment.
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| Overall design |
mRNA profiles of untreated and PEN221, Belinostat or DMSO treated NPC cell line C666_1 at 24h and 72h post treatment.
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| Contributor(s) |
Lechner M, Steele CD, Schartinger VH |
| Citation(s) |
33402692 |
| |
| Submission date |
Nov 05, 2020 |
| Last update date |
Jan 19, 2021 |
| Contact name |
Matt Lechner |
| E-mail(s) |
[email protected]
|
| Organization name |
UCL
|
| Street address |
72 Huntley Street
|
| City |
London |
| State/province |
Please Select |
| ZIP/Postal code |
WC1E 6DD |
| Country |
United Kingdom |
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| Platforms (1) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA674768 |
| SRA |
SRP291270 |
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