|
| Status |
Public on Oct 24, 2020 |
| Title |
Identification of required host factors for SARS-CoV-2 infection in human cells |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
We performed a genome-wide CRISPR knockout screen to identify human genes required for SARS-CoV-2 infection.
|
| |
|
| Overall design |
Human A549-ACE2 CRISPR-Cas9 perturbed cells were infected with SARS-CoV-2 at two MOIs (0.01 and 0.3), and cells were collected for genomic DNA isolation 6 days post-infection.
|
| Web link |
https://doi.org/10.1016/j.cell.2020.10.030
|
| |
|
| Contributor(s) |
Daniloski Z, Jordan TX, tenOever BR, Sanjana NE |
| Citation(s) |
33147445, 33880488 |
| |
| Submission date |
Sep 21, 2020 |
| Last update date |
May 27, 2021 |
| Contact name |
Zharko Daniloski |
| E-mail(s) |
[email protected]
|
| Organization name |
New York University
|
| Department |
Biology
|
| Street address |
1 Washington square village, 2P
|
| City |
New York City |
| State/province |
New York |
| ZIP/Postal code |
10012 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (4)
|
|
| Relations |
| Reanalyzed by |
GSE175666 |
| BioProject |
PRJNA664769 |
| SRA |
SRP284267 |
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