|
| Status |
Public on Sep 11, 2020 |
| Title |
Transcription landscape of adipose tissue changes in response to telomerase knockout in mesenchymal progenitors |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We generated mice with telomerase (TERT) gene knock-out (KO) that undergo premature telomere shortening in adipose stromal cells expressing Pdgfra or Pdgfrb. Stromal vascular cells were isolated from inguinal adipose tissue of Pdgfra-Cre; TERT fl/fl mice (Sample name A_SAT), Pdgfrb-Cre; TERT fl/fl mice (Sample name KO_SAT), and of control TERT WT mice (Sample name PBS_SAT).
|
| |
|
| Overall design |
scRNAseq analysis of subcutaneous adipose tissue stromal vascular cells was performed.
|
| |
|
| Contributor(s) |
Kolonin M, Gao Z, Daquinag A, Dai Y |
| Citation(s) |
33324010 |
| |
| Submission date |
Sep 11, 2020 |
| Last update date |
Dec 29, 2020 |
| Contact name |
Yulin Dai |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Texas health science center at Houston
|
| Department |
School of Biomedical Informatics
|
| Street address |
7000 fannin, suite 600
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA662910 |
| SRA |
SRP282041 |
