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| Status |
Public on May 26, 2021 |
| Title |
Changes of H3K9ac and H3K27ac recruitment in pachytene spermatocytes and round spermatids from testes-specific HDAC3-depleted mice and genome-wide maps of HDAC3,NCOR and Sox30 in wild-type and Sox30 KO testes |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We reported changes in the recruitment of H3K9ac and H3K27ac in HDAC3-depleted mouse testes in the late meiotic and early haploid stages. We also investigated genome-wide occupancy of HDAC3, NCOR and Sox30 to the mouse testes from wild-type and Sox30 KO mice.
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| Overall design |
ChIP-seq of H3K9ac and H3K27ac in pachytene spermatocytes and round spermatids isolated from adult wild-type and HDAC3-depleted mice. ChIP-seq profiling of HDAC3, NCOR and Sox30 in mouse testes from wild-type and Sox30 KO mice at postnatal day 20.
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| Contributor(s) |
Kang Z, Yin H, Ye L |
| Citation(s) |
33939832 |
| |
| Submission date |
Jun 23, 2020 |
| Last update date |
May 28, 2021 |
| Contact name |
Lan Ye |
| Organization name |
Nanjing Medical University
|
| Street address |
B112 Xuehai Building,101 Longmian Avenue, Jiangning district
|
| City |
Nanjing |
| State/province |
Jiangsu |
| ZIP/Postal code |
211166 |
| Country |
China |
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| Platforms (1) |
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| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE153065 |
Changes of H3K9ac and H3K27ac recruitment and gene expression in pachytene spermatocytes and round spermatids depleted of HDAC3 |
|
| Relations |
| BioProject |
PRJNA641377 |
| SRA |
SRP268469 |
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