|
| Status |
Public on Jan 11, 2021 |
| Title |
Remodeling of white fat during browning involves YBX1 to drive thermogenic commitment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Effects of YBX1 activation in PPARγ-indcuded C3H/10T1/2-SAM pre-adipocytes on the transcriptome of cells during early differentation stages
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| Overall design |
C3H/10T1/2-SAM pre-adipocytes containing dCas9-VP64 and MS2-P65-HSF1 were transfected with guide RNA taregting PPARγ or a combination of guides taregting PPARγ and YBX1 two days before differentiation start to model gain of funtion in pre-adipocytes. Transcriptome was analysed for day 0, day 2 and day 4 of differentiation.
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| |
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| Contributor(s) |
Plucińska K, Chehabi GN, Altintas A, Barrès R, Emanuelli B |
| Citation(s) |
33285300 |
| |
| Submission date |
Apr 22, 2020 |
| Last update date |
Jan 11, 2021 |
| Contact name |
Ali Altintas |
| E-mail(s) |
[email protected]
|
| Organization name |
Copenhagen University
|
| Department |
NNF Center for Basic Metabolic Research
|
| Lab |
Integrative Physiology
|
| Street address |
Blegdamsvej 3B
|
| City |
Copenhagen |
| ZIP/Postal code |
2200 |
| Country |
Denmark |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (51)
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| Relations |
| BioProject |
PRJNA627345 |
| SRA |
SRP257862 |
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