|
| Status |
Public on Nov 28, 2020 |
| Title |
Inhibition of PRC2 activity by H3K36 methylation |
| Organism |
Drosophila melanogaster |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We provide evidence that Drosophila H3K36A and H3K36R mutant embryos as well as H3K36R mutant larvae show altered H3K36me2 and H3K27me3 ChIP-seq profiles.
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| |
|
| Overall design |
Analyis of H3K36me2 and H3K27me3 ChIP-seq profiles and read coverage across gene bodies in H3K36A and H3K36R mutant embryos and H3K36R larvae as compared to the corresponding wild-type references.
|
| Web link |
https://elifesciences.org/articles/61964
|
| |
|
| Contributor(s) |
Müller J, Bonnet J |
| Citation(s) |
33211010 |
| |
| Submission date |
Apr 07, 2020 |
| Last update date |
Dec 22, 2020 |
| Contact name |
Jürg Müller |
| Organization name |
Max Planck Institute of Biochemistry
|
| Street address |
Am Klopferspitz
|
| City |
Martinsried |
| State/province |
Bavaria |
| ZIP/Postal code |
82152 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL19132 |
Illumina NextSeq 500 (Drosophila melanogaster) |
|
| Samples (30)
|
|
| Relations |
| BioProject |
PRJNA623606 |
| SRA |
SRP255628 |
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