|
| Status |
Public on Jun 21, 2019 |
| Title |
Transcriptome data after TRIM28 knockdown in A375 melanoma cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
TRIM28 is a bromodomain protein implicated in the regulation of tumor growth. TRIM28 regulates gene expression by recruiting epigenetic writers including HDACs, SETDB1 and HP1.
To determine the role of TRIM28 in melanoma cells we knocked down TRIM28 using lentiviral shRNA constructs followed by gene expression analysis using HTA 2.0 GeneChip.
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| |
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| Overall design |
Eight samples were analyzed. Four control samples (non-targeting control shRNA) and four experimental samples (TRIM28-specific shRNA).
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| |
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| Contributor(s) |
Espinosa A, Nyberg W |
| Citation(s) |
36341538 |
| |
| Submission date |
Jun 20, 2019 |
| Last update date |
Nov 07, 2022 |
| Contact name |
Alexander Espinosa |
| Organization name |
Karolinska Institutet
|
| Department |
Dept of Medicine
|
| Street address |
Visionsgatan 18
|
| City |
Stockholm |
| ZIP/Postal code |
SE-17164 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA549885 |
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