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| Status |
Public on Sep 20, 2018 |
| Title |
Characterization of ST2+ and ST2- mTh cells in helminth infection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
CD4+T cells are differentiated into Th1, Th2, Th17 and Treg cells after Antigen presentation by other cell types such as dendritic cells, macrophages and B cells in Lymph nodes. Those differentiated CD4+T cells are subdivided into cell subsets by their producing cytokines and surface markers. We recently identified that ST2 expressing Th2 cells highly produced IL-5 comparing to ST2- Th2 cells in helminth infection. In this study, we investigated the RNAseq analysis to characterize these Th2 cells.
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| |
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| Overall design |
Characterization of ST2+ and ST2- mTh cells are assessed by RNA-seq.
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| |
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| Contributor(s) |
Obata-Ninomiya K, Onodera A, Kato M, Nakayama T |
| Citation(s) |
30275296 |
| |
| Submission date |
Sep 19, 2018 |
| Last update date |
Dec 20, 2018 |
| Contact name |
Atsushi Onodera |
| Organization name |
Chiba University
|
| Department |
Immunology
|
| Street address |
Chuo-ku Inohana 1-8-1
|
| City |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA491848 |
| SRA |
SRP162113 |
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