|
| Status |
Public on Sep 02, 2019 |
| Title |
Stag2 regulates hematopoietic differentiation and self-renewal through alterations in gene expression and topological control |
| Organism |
Mus musculus |
| Experiment type |
Other
|
| Summary |
We performed HiC analyzed on wildtype and Stag2 knock-out hematopoietic progeitor cells and integrated with Stag2 ChIP-seq and RNAseq data to identy genes whose expression and tological structures are regulated by Stag2 during hematopoietic differentiation and self-renewal.
|
| |
|
| Overall design |
Comparing HiC profiles of two wildtype hematopoietic progenitor cells with two Stag2 KO cells.
|
| |
|
| Contributor(s) |
Liu Y, Dekker J |
| Citation(s) |
31495782 |
| |
| Submission date |
Sep 02, 2018 |
| Last update date |
Oct 03, 2021 |
| Contact name |
Job Dekker |
| E-mail(s) |
[email protected]
|
| Phone |
508-856-4371
|
| Organization name |
University of Massachusetts Medical School
|
| Department |
Program in Systems Biology
|
| Lab |
Dekker Lab
|
| Street address |
368 Plantation Street, AS5-1049
|
| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE135031 |
Stag1 and Stag2 regulate cell fate decisions in hematopoiesis through non-redundant topological control |
|
| Relations |
| BioProject |
PRJNA488956 |
| SRA |
SRP159429 |
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