We performed a retrospective analysis of the SweBCG 91-RT trial, which randomized women with node-negative stage I-IIA breast cancer to whole breast radiotherapy or no radiotherapy following breast-conserving surgery with minimal use of adjuvant systemic treatment. Primary tumors were profiled with the GeneChip Human Exon 1.0 ST microarray.
Overall design
RNA was isolated from FFPE tissue specimens of the SweBCG 91-RT trial and whole transcriptome profiling was performed. Profiling was successful for 765 patients.
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