|
| Status |
Public on Mar 01, 2019 |
| Title |
Identification of HOXB13 target genes responsive to BET inhibitors |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We identified BRD4 as an epigenetic regulator of the prostate lineage specific gene HOXB13 during progression of the disease from an androgen
dependent to an androgen independent state.
|
| |
|
| Overall design |
Integrative analysis- we compared genes whose expression was significantly impacted either (up or downregulated) as a result of HOXB13 knockdown and were also sensitive to BET inhibition
|
| |
|
| Contributor(s) |
Mahajan K, Perera R |
| Citation(s) |
30242092 |
| |
| Submission date |
Mar 24, 2018 |
| Last update date |
Mar 01, 2019 |
| Contact name |
Kiran Mahajan |
| E-mail(s) |
[email protected]
|
| Phone |
3142737728
|
| Organization name |
Washington University
|
| Department |
Surgery
|
| Lab |
Kiran Mahajan Lab
|
| Street address |
CB 8242 600 South Euclid Ave
|
| City |
St. Louis |
| State/province |
Missouri |
| ZIP/Postal code |
63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA445557 |
| SRA |
SRP136392 |
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