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| Status |
Public on Sep 30, 2018 |
| Title |
Molecular mechanisms and potential therapeutic drugs linking to cetuximab-induced reactions in human cells (HaCaT cells) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To obtain differentially expressed genes associated with cetuximab induced cytotoxicity we analyzed RNA samples using whole genome microarray expression profiling as a discovery platform to identify genes . Two kinds of RNA samples were extracted from HaCaT and HEK 293 cell; without cetuximab and incubation for 24 hours with 1.63μM (fixed maintenance dose) cetuximab.
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| Overall design |
Cetuximab induced cytotoxicity gene expression in HaCaT cells was measured at 24 hours exposure to doses of 0 and 1.63 µM cetuximab.
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| Contributor(s) |
Sawai Y, Uzawa K |
| Citation missing |
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| Submission date |
Mar 15, 2018 |
| Last update date |
Oct 02, 2018 |
| Contact name |
Yuki Sawai |
| E-mail(s) |
[email protected]
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| Organization name |
Graduate School of Medicine, Chiba University
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| Department |
Department of Oral Science
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| Street address |
1-8-1 Inohana, Chuo-ku
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| City |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
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| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE111887 |
Molecular mechanisms and potential therapeutic drugs linking to cetuximab-induced reactions in human cells |
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| Relations |
| BioProject |
PRJNA438485 |
