|
| Status |
Public on May 13, 2019 |
| Title |
Single cell expression profiling of murine p53-/- shPU.1 AML cells following PU.1 restoration |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We have utilized advanced RNAi technology to dynamically restore endogenous PU.1 expression in p53-deficient AML cells.
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| |
|
| Overall design |
RNA-seq was performed on individual clone 2 AML246 cells either untreated or treated with doxycycline for 14 days, compared with normal mouse peripheral blood neutrophils.
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| |
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| Contributor(s) |
Su S, Oxley EP, McKenzie MD, Baldwin TM, Naik SH, Zalcenstein DA, Dickins RA, Ritchie ME |
| Citation(s) |
31374198 |
| |
| Submission date |
Jan 11, 2018 |
| Last update date |
Aug 05, 2019 |
| Contact name |
Shian Su |
| E-mail(s) |
[email protected]
|
| Organization name |
Walter and Eliza Hall Institute of Medical Research
|
| Department |
Molecular Medicine
|
| Lab |
Ritchie Lab
|
| Street address |
1G Royal Parade
|
| City |
Melbourne |
| State/province |
Victoria |
| ZIP/Postal code |
3052 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (1) |
| GSM2931660 |
Clone 2 AML246 cells untreated and Doxycline treated |
|
| This SubSeries is part of SuperSeries: |
| GSE76934 |
Reversible transitions between transformed and differentiated states in AML |
|
| Relations |
| BioProject |
PRJNA429645 |
| SRA |
SRP128912 |
