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| Status |
Public on Apr 13, 2018 |
| Title |
Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We examined effects of early life stress (ELS) and environmental enrichment (EE) during development on BACHD rat striatal gene expression using RNA sequencing
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| |
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| Overall design |
We used a 2×3 factorial design with two genotypes (wildtype, WT; transgene, TG) and three environmental conditions (standard environment, SE; enriched environment, EE; early life stress, ELS) to assess effects of environmental enrichment and early life stress on striatal gene expression of 2-month-old WT and BACHD rats
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| |
|
| Contributor(s) |
Schulze-Hentrich JM, Hentrich T |
| Citation(s) |
29643462 |
| |
| Submission date |
Nov 22, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Julia Maria Schulze-Hentrich |
| E-mail(s) |
[email protected]
|
| Organization name |
Saarland University
|
| Department |
Genetics and Epigenetics
|
| Street address |
Campus, Building A2.4
|
| City |
Saarbrücken |
| ZIP/Postal code |
66123 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL18694 |
Illumina HiSeq 2500 (Rattus norvegicus) |
|
| Samples (36)
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| Relations |
| BioProject |
PRJNA419484 |
| SRA |
SRP125460 |
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