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    ram-2 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174687, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ram-2
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00004300
    Locus tag
    CELE_F38A3.2
    See related
    AllianceGenome:WB:WBGene00004300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Involved in nematode male tail tip morphogenesis and sensory organ development. Predicted to be located in membrane. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ram-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (11015589..11016881, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Pre-mRNA-splicing factor CWC22 homolog Neighboring gene Neuropeptide-Like Protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of ram-5 in the structural cell is required for sensory ray morphogenesis in Caenorhabditis elegans male tail. Yu RY, et al. EMBO J, 2000 Jul 17. PMID 10899109, Free PMC Article
    2. Mutations with sensory ray defect unmask cuticular glycoprotein antigens in Caenorhabditis elegans male tail. Ko FC, et al. Dev Growth Differ, 2000 Feb. PMID 10831045
    3. Stress-induced phenocopy of C. elegans defines functional steps of sensory organ differentiation. Chow KL, et al. Dev Growth Differ, 1999 Oct. PMID 10545035
    4. Complementation. Yook K. WormBook, 2005 Oct 6. PMID 18023121, Free PMC Article
    5. Properties of a class of genes required for ray morphogenesis in Caenorhabditis elegans. Baird SE, et al. Genetics, 1990 Oct. PMID 2245913, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nematode male tail tip morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory organ development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_496362.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11015589..11016881 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063961.5 → NP_496362.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496362.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20136
      Conserved Domains (1) summary
      smart01088
      Location:19 → 71
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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