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Conserved domains on  [gi|17533809|ref|NP_496362|]
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Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 19-71 1.90e-19

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 79.82  E-value: 1.90e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17533809     19 KVAFFGICISTVATLTAIVAIPLLYNYMQHVQSTLQTEVDFCKHRTNGLFDQY 71
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 128-270 9.94e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.19  E-value: 9.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533809  128 DGSDGKDGLSGPDGQPGADADPEATPSEADfcfdcpagpPGPAGNPGPKGPSGNAGADGQPGAPGNAGAAGAPGAPGPAG 207
Cdd:NF038329 167 QGEAGPQGPAGKDGEAGAKGPAGEKGPQGP---------RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP 237

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17533809  208 pDGQPGSTGQDGAPGVVEEvavpagpagaPGPAGAPGADGAAGAPGQPGQDGPQGPAGDAGSD 270
Cdd:NF038329 238 -DGDPGPTGEDGPQGPDGP----------AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKD 289
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 19-71 1.90e-19

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 79.82  E-value: 1.90e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17533809     19 KVAFFGICISTVATLTAIVAIPLLYNYMQHVQSTLQTEVDFCKHRTNGLFDQY 71
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 22-70 9.19e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 67.10  E-value: 9.19e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17533809    22 FFGICISTVATLTAIVAIPLLYNYMQHVQSTLQTEVDFCKHRTNGLFDQ 70
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNE 49
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 128-270 9.94e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.19  E-value: 9.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533809  128 DGSDGKDGLSGPDGQPGADADPEATPSEADfcfdcpagpPGPAGNPGPKGPSGNAGADGQPGAPGNAGAAGAPGAPGPAG 207
Cdd:NF038329 167 QGEAGPQGPAGKDGEAGAKGPAGEKGPQGP---------RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP 237

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17533809  208 pDGQPGSTGQDGAPGVVEEvavpagpagaPGPAGAPGADGAAGAPGQPGQDGPQGPAGDAGSD 270
Cdd:NF038329 238 -DGDPGPTGEDGPQGPDGP----------AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKD 289
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 19-71 1.90e-19

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 79.82  E-value: 1.90e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17533809     19 KVAFFGICISTVATLTAIVAIPLLYNYMQHVQSTLQTEVDFCKHRTNGLFDQY 71
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 22-70 9.19e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 67.10  E-value: 9.19e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17533809    22 FFGICISTVATLTAIVAIPLLYNYMQHVQSTLQTEVDFCKHRTNGLFDQ 70
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNE 49
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 128-270 9.94e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.19  E-value: 9.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533809  128 DGSDGKDGLSGPDGQPGADADPEATPSEADfcfdcpagpPGPAGNPGPKGPSGNAGADGQPGAPGNAGAAGAPGAPGPAG 207
Cdd:NF038329 167 QGEAGPQGPAGKDGEAGAKGPAGEKGPQGP---------RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP 237

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17533809  208 pDGQPGSTGQDGAPGVVEEvavpagpagaPGPAGAPGADGAAGAPGQPGQDGPQGPAGDAGSD 270
Cdd:NF038329 238 -DGDPGPTGEDGPQGPDGP----------AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKD 289
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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