zdhhc3a zinc finger DHHC-type palmitoyltransferase 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zdhhc3aprovided by ZNC
Official Full Name: zinc finger DHHC-type palmitoyltransferase 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-484
See related: Ensembl:ENSDARG00000010981 AllianceGenome:ZFIN:ZDB-GENE-040718-484
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zdhhc3; zgc:92587; tdsubc_2d6; ik:tdsubc_2d6; xx:tdsubc_2d6
Summary: Enables S-acyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC3 (zinc finger DHHC-type palmitoyltransferase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (39196800..39233451)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (39246589..39283419)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables S-acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-cysteine S-myristoyltransferase activity	IC Inferred by Curator more info	PubMed
enables protein-cysteine S-palmitoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-cysteine S-palmitoyltransferase activity	IC Inferred by Curator more info	PubMed
enables protein-cysteine S-palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-cysteine S-palmitoyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-cysteine S-stearoyltransferase activity	IC Inferred by Curator more info	PubMed
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptidyl-L-cysteine S-palmitoylation	IDA Inferred from Direct Assay more info	PubMed
involved_in peptidyl-L-cysteine S-palmitoylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: palmitoyltransferase ZDHHC3-A

Names: acyltransferase ZDHHC3A; palmitoyltransferase ZDHHC3a; zinc finger DHHC domain-containing protein 3; zinc finger DHHC-type containing 3a; zinc finger, DHHC-type containing 3

NP_001002725.1

EC 2.3.1.225

XP_005158266.1

EC 2.3.1.225

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002725.1 → NP_001002725.1 palmitoyltransferase ZDHHC3-A

See identical proteins and their annotated locations for NP_001002725.1

Status: PROVISIONAL

Source sequence(s)

BC076087

UniProtKB/Swiss-Prot

F1RE57, Q6DH92

Related

ENSDARP00000025104.6, ENSDART00000017017.8

Conserved Domains (1) summary

pfam01529
Location:127 → 251

zf-DHHC; DHHC palmitoyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

39196800..39233451

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005158209.5 → XP_005158266.1 palmitoyltransferase ZDHHC3-A isoform X1

UniProtKB/Swiss-Prot

F1RE57, Q6DH92

UniProtKB/TrEMBL

A0A8M2B4K7

Conserved Domains (1) summary

pfam01529
Location:127 → 253

zf-DHHC; DHHC palmitoyltransferase