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    apba2b amyloid beta (A4) precursor protein-binding, family A, member 2b [ Danio rerio (zebrafish) ]

    Gene ID: 327160, updated on 9-Dec-2024

    Summary

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    Official Symbol
    apba2bprovided by ZNC
    Official Full Name
    amyloid beta (A4) precursor protein-binding, family A, member 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5371
    See related
    Ensembl:ENSDARG00000060639 AllianceGenome:ZFIN:ZDB-GENE-030131-5371
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    apba2; fd15a04; wu:fd15a04
    Summary
    Predicted to enable amyloid-beta binding activity. Predicted to be involved in chemical synaptic transmission. Predicted to be active in cytoplasm; dendritic spine; and plasma membrane. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See apba2b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (30787937..30915965)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (30516742..30644813)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) Neighboring gene methylmalonyl CoA epimerase Neighboring gene si:dkey-1h4.4 Neighboring gene sorbitol dehydrogenase Neighboring gene telomere repeat binding bouquet formation protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Recent assembly of an imprinted domain from non-imprinted components. Rapkins RW, et al. PLoS Genet, 2006 Oct. PMID 17069464, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    amyloid beta A4 precursor protein-binding family A member 2; amyloid-beta A4 precursor protein-binding family A member 2
    Names
    amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      30787937..30915965
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168928.5 → XP_005168985.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      See identical proteins and their annotated locations for XP_005168985.1

      UniProtKB/TrEMBL
      A0A8M2BG86
      Conserved Domains (2) summary
      cd01208
      Location:447 → 620
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:746 → 817
      PDZ; PDZ domain (Also known as DHR or GLGF)

    2. XM_002662843.7 → XP_002662889.2  amyloid-beta A4 precursor protein-binding family A member 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5NS70, A0A8M1RKA4
      Related
      ENSDARP00000142680.1, ENSDART00000174000.2
      Conserved Domains (2) summary
      cd01208
      Location:447 → 619
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:745 → 816
      PDZ; PDZ domain (Also known as DHR or GLGF)

    3. XM_005168930.5 → XP_005168987.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M2BGT9
      Related
      ENSDARP00000148950.1, ENSDART00000193106.1
      Conserved Domains (2) summary
      cd01208
      Location:447 → 608
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:734 → 805
      PDZ; PDZ domain (Also known as DHR or GLGF)

    4. XM_005168931.5 → XP_005168988.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M2BG77, F1Q9E4
      Related
      ENSDARP00000080096.6, ENSDART00000085661.6
      Conserved Domains (2) summary
      cd01208
      Location:447 → 607
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:733 → 804
      PDZ; PDZ domain (Also known as DHR or GLGF)

    5. XM_005168929.5 → XP_005168986.1  amyloid-beta A4 precursor protein-binding family A member 2 isoform X1

      See identical proteins and their annotated locations for XP_005168986.1

      UniProtKB/TrEMBL
      A0A8M2BG86
      Conserved Domains (2) summary
      cd01208
      Location:447 → 620
      PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain
      pfam00595
      Location:746 → 817
      PDZ; PDZ domain (Also known as DHR or GLGF)
    Nucleotide Protein Strain
    Heading Accession and Version

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