KLCR1 Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: KLCR1
Official Full Name: Tetratricopeptide repeat (TPR)-like superfamily protein
Primary source: TAIR:AT4G10840
Locus tag: AT4G10840
See related: Araport:AT4G10840
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F25I24.50; F25I24_50; kinesin light chain-related 1
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Genomic context

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See KLCR1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 4

Sequence:: Chromosome: 4; NC_003075.7 (6656374..6659265)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

IQD1 may act as a scaffold protein, recruiting cargo to kinesin motors (KLCR1) for directional transport along microtubules. [KLCR1] [kinesin light chain-related protein-1]
Title: Arabidopsis calmodulin-binding protein IQ67-domain 1 localizes to microtubules and interacts with kinesin light chain-related protein-1.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_117152.5

Supported by ESTs:

NM_202801.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with cortical microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Tetratricopeptide repeat (TPR)-like superfamily protein

NP_192822.1

Tetratricopeptide repeat (TPR)-like superfamily protein; FUNCTIONS IN: binding; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G27960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NP_974530.1

Tetratricopeptide repeat (TPR)-like superfamily protein; FUNCTIONS IN: binding; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G27960.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

6656374..6659265

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_117152.5 → NP_192822.1 Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_192822.1

Status: REVIEWED

UniProtKB/Swiss-Prot

F4JMG6, O81629, Q8LCN6

UniProtKB/TrEMBL

A0A178UXD8, A0A5S9XRE7

Conserved Domains (3) summary

COG0457
Location:229 → 500

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

sd00006
Location:140 → 168

TPR; TPR repeat [structural motif]

pfam13424
Location:476 → 548

TPR_12; Tetratricopeptide repeat
NM_202801.1 → NP_974530.1 Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_974530.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O81629

Conserved Domains (6) summary

sd00006
Location:140 → 168

TPR; TPR repeat [structural motif]

cd15832
Location:322 → 361

SNAP; TPR repeat [structural motif]

pfam13374
Location:139 → 178

TPR_10; Tetratricopeptide repeat

pfam13414
Location:186 → 255

TPR_11; TPR repeat

pfam13424
Location:305 → 381

TPR_12; Tetratricopeptide repeat

cl24038
Location:322 → 499

SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family