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    NFAT5 nuclear factor of activated T cells 5 [ Sceloporus undulatus (fence lizard) ]

    Gene ID: 121937529, updated on 22-Mar-2024

    Summary

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    Gene symbol
    NFAT5
    Gene description
    nuclear factor of activated T cells 5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sceloporus undulatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Phrynosomatidae; Phrynosomatinae; Sceloporus
    Orthologs
    human mouse all
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    Genomic context

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    See NFAT5 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    100 current SceUnd_v1.1 (GCF_019175285.1) 8 NC_056529.1 (22479950..22528037)

    Chromosome 8 - NC_056529.1Genomic Context describing neighboring genes Neighboring gene cytochrome b5 type B Neighboring gene uncharacterized LOC121914887 Neighboring gene NAD(P)H quinone dehydrogenase 1 Neighboring gene NIN1 (RPN12) binding protein 1 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056529.1 Chromosome 8 Reference SceUnd_v1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor of activated T-cells 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sceloporus undulatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference SceUnd_v1.1

    Genomic

    1. NC_056529.1 Reference SceUnd_v1.1

      Range
      22479950..22528037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042480787.1 → XP_042336721.1  nuclear factor of activated T-cells 5 isoform X3

      Conserved Domains (3) summary
      cd07882
      Location:286 → 446
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:683 → 804
      PRK11281; mechanosensitive channel MscK
      cd01178
      Location:450 → 549
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    2. XM_042480786.1 → XP_042336720.1  nuclear factor of activated T-cells 5 isoform X2

      Conserved Domains (4) summary
      cd07882
      Location:286 → 446
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:696 → 817
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:580 → 755
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:450 → 549
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    3. XM_042480791.1 → XP_042336725.1  nuclear factor of activated T-cells 5 isoform X5

      Conserved Domains (3) summary
      cd07882
      Location:286 → 446
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:657 → 778
      PRK11281; mechanosensitive channel MscK
      cd01178
      Location:450 → 549
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    4. XM_042480785.1 → XP_042336719.1  nuclear factor of activated T-cells 5 isoform X1

      Conserved Domains (4) summary
      cd07882
      Location:286 → 446
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:722 → 843
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:606 → 781
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:450 → 549
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    5. XM_042480790.1 → XP_042336724.1  nuclear factor of activated T-cells 5 isoform X4

      Conserved Domains (4) summary
      cd07882
      Location:232 → 392
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:668 → 789
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:552 → 727
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:396 → 495
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    6. XM_042480794.1 → XP_042336728.1  nuclear factor of activated T-cells 5 isoform X6

      Conserved Domains (4) summary
      cd07882
      Location:210 → 370
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:646 → 767
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:530 → 705
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:374 → 473
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    7. XM_042480798.1 → XP_042336732.1  nuclear factor of activated T-cells 5 isoform X7

      Conserved Domains (3) summary
      cd07882
      Location:74 → 234
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK14949
      Location:394 → 569
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:238 → 337
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    8. XM_042480796.1 → XP_042336730.1  nuclear factor of activated T-cells 5 isoform X7

      Conserved Domains (3) summary
      cd07882
      Location:74 → 234
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK14949
      Location:394 → 569
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:238 → 337
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    9. XM_042480789.1 → XP_042336723.1  nuclear factor of activated T-cells 5 isoform X4

      Conserved Domains (4) summary
      cd07882
      Location:232 → 392
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:668 → 789
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:552 → 727
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:396 → 495
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    10. XM_042480788.1 → XP_042336722.1  nuclear factor of activated T-cells 5 isoform X4

      Conserved Domains (4) summary
      cd07882
      Location:232 → 392
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:668 → 789
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:552 → 727
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:396 → 495
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    11. XM_042480795.1 → XP_042336729.1  nuclear factor of activated T-cells 5 isoform X7

      Conserved Domains (3) summary
      cd07882
      Location:74 → 234
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK14949
      Location:394 → 569
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:238 → 337
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    12. XM_042480793.1 → XP_042336727.1  nuclear factor of activated T-cells 5 isoform X6

      Conserved Domains (4) summary
      cd07882
      Location:210 → 370
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK11281
      Location:646 → 767
      PRK11281; mechanosensitive channel MscK
      PRK14949
      Location:530 → 705
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:374 → 473
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    13. XM_042480797.1 → XP_042336731.1  nuclear factor of activated T-cells 5 isoform X7

      Conserved Domains (3) summary
      cd07882
      Location:74 → 234
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK14949
      Location:394 → 569
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:238 → 337
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    14. XM_042480799.1 → XP_042336733.1  nuclear factor of activated T-cells 5 isoform X8

      Conserved Domains (3) summary
      cd07882
      Location:13 → 173
      RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)
      PRK14949
      Location:333 → 508
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
      cd01178
      Location:177 → 276
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
    Nucleotide Protein
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