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    Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 84406, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hs3st1provided by RGD
    Official Full Name
    heparan sulfate-glucosamine 3-sulfotransferase 1provided by RGD
    Primary source
    RGD:71084
    See related
    EnsemblRapid:ENSRNOG00000068537 AllianceGenome:RGD:71084
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    3OST-I
    Summary
    Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to be involved in glycosaminoglycan biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Predicted to be active in Golgi apparatus. Orthologous to human HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Hs3st1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (75398101..75429628)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (71185826..71223263)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (75880410..75881346)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096628 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC102547538 Neighboring gene uncharacterized LOC120096629

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi lumen IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heparan sulfate glucosamine 3-O-sulfotransferase 1
    Names
    heparan sulfate (glucosamine) 3-O-sulfotransferase 1
    heparan sulfate 3-O-sulfotransferase 1
    heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
    heparan sulfate glucosamine 3-O-sulfotransferase I
    NP_445843.2
    XP_038948434.1
    XP_063129752.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053391.2NP_445843.2  heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A221CBA4, A6IJR8, G3V7E2
      Conserved Domains (1) summary
      pfam00685
      Location:59296
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      75398101..75429628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039092506.2XP_038948434.1  heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A221CBA4, A6IJR8, G3V7E2
      Related
      ENSRNOP00000094638.1, ENSRNOT00000105004.2
      Conserved Domains (1) summary
      pfam00685
      Location:59296
      Sulfotransfer_1; Sulfotransferase domain
    2. XM_063273682.1XP_063129752.1  heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A221CBA4, A6IJR8, G3V7E2
      Related
      ENSRNOP00000091056.1, ENSRNOT00000098441.2