U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    C27H6.9 Mitochondrial genome maintenance exonuclease 1 [ Caenorhabditis elegans ]

    Gene ID: 6418702, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    C27H6.9
    Official Full Name
    Mitochondrial genome maintenance exonuclease 1
    Primary source
    WormBase:WBGene00077500
    Locus tag
    CELE_C27H6.9
    See related
    AllianceGenome:WB:WBGene00077500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Orthologous to human MGME1 (mitochondrial genome maintenance exonuclease 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See C27H6.9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (9982868..9983932)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene RuvB-like 1 Neighboring gene Schlafen-like protein 1 Neighboring gene TPR_REGION domain-containing protein Neighboring gene MYG1 protein C27H6.8 Neighboring gene Piwi domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded DNA exodeoxyribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA exodeoxyribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial genome maintenance IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Mitochondrial genome maintenance exonuclease 1
    NP_001122867.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9982868..9983932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129395.2 → NP_001122867.1  Mitochondrial genome maintenance exonuclease 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122867.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9QY30
      Conserved Domains (1) summary
      cl00641
      Location:163 → 264
      Cas4_I-A_I-B_I-C_I-D_II-B; CRISPR/Cas system-associated protein Cas4
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools