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    ESP epithiospecifier protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841842, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ESP
    Official Full Name
    epithiospecifier protein
    Primary source
    TAIR:AT1G54040
    Locus tag
    AT1G54040
    See related
    Araport:AT1G54040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    epithiospecifier protein; EPITHIOSPECIFYING SENESCENCE REGULATOR; ESR; F15I1.12; F15I1_12; TASTY
    Summary
    Epithiospecifier protein, interacts with WRKY53. Involved in pathogen resistance and leaf senescence.
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    Genomic context

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    See ESP in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (20170715..20173949, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene miscRNA Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene 6B-interacting protein 1-like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ecotype dependent expression and alternative splicing of epithiospecifier protein (ESP) in Arabidopsis thaliana. Kissen R, et al. Plant Mol Biol, 2012 Mar. PMID 22228407
    2. Cell- and tissue-specific localization and regulation of the epithiospecifier protein in Arabidopsis thaliana. Burow M, et al. Plant Mol Biol, 2007 May. PMID 17390109
    3. The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory. Lambrix V, et al. Plant Cell, 2001 Dec. PMID 11752388, Free PMC Article
    4. Crystal structure of the Epithiospecifier Protein, ESP from Arabidopsis thaliana provides insights into its product specificity. Zhang W, et al. Biochem Biophys Res Commun, 2016 Sep 16. PMID 27498030
    5. The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium. Miao Y, et al. Plant Cell, 2007 Mar. PMID 17369373, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. expression during growth cycle in different organs and alternative splicing of epithiospecifier protein
      Title: Ecotype dependent expression and alternative splicing of epithiospecifier protein (ESP) in Arabidopsis thaliana.
    2. These results suggest that WRKY53 and ESR mediate negative crosstalk between pathogen resistance and senescence, which is most likely governed by the jasmonic acid and salicylic acid equilibrium.
      Title: The antagonist function of Arabidopsis WRKY53 and ESR/ESP in leaf senescence is modulated by the jasmonic and salicylic acid equilibrium.
    3. ESP-expressing cells in various organs and several developmental stages of different Arabidopsis thaliana ecotypes are identified by immunolocalization.
      Title: Cell- and tissue-specific localization and regulation of the epithiospecifier protein in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001333628.1
    NM_104281.3
    NM_180632.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables enzyme regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    epithiospecifier protein
    NP_175806.3
    • epithiospecifier protein (ESP); FUNCTIONS IN: enzyme regulator activity; INVOLVED IN: response to jasmonic acid stimulus, glucosinolate catabolic process, leaf senescence, defense response to bacterium; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: nitrile specifier protein 1 (TAIR:AT3G16400.2); Has 9344 Blast hits to 5467 proteins in 352 species: Archae - 6; Bacteria - 442; Metazoa - 5815; Fungi - 649; Plants - 1336; Viruses - 16; Other Eukaryotes - 1080 (source: NCBI BLink).
    NP_850963.1
    • epithiospecifier protein (ESP); FUNCTIONS IN: enzyme regulator activity; INVOLVED IN: response to jasmonic acid stimulus, glucosinolate catabolic process, leaf senescence, defense response to bacterium; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: nitrile specifier protein 1 (TAIR:AT3G16400.2); Has 5483 Blast hits to 3741 proteins in 298 species: Archae - 4; Bacteria - 264; Metazoa - 3381; Fungi - 416; Plants - 905; Viruses - 2; Other Eukaryotes - 511 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20170715..20173949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104281.3 → NP_175806.3  epithiospecifier protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175806.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0LYN4, B0LYN5, B0LYN6, B0LYN7, B0LYN8, B0LYP0, B0LYP2, B0LYP4, B0LYP6, B0LYS4, B0LYT0, B0LYT3, B0LYT8, B0LYT9, B0LYU6, B0LYU8, B0LYV4, B0LYW2, B0LYW3, B0LYW5, B0LYW7, B0LYX3, B0LYX4, B0LYX6, B0LYX7, Q39104, Q8RY71, Q93VB6, Q9SYG0
      UniProtKB/TrEMBL
      A0A178WKF9, A0A5S9WPH8, A0A7G2E231
      Conserved Domains (2) summary
      PLN02153
      Location:1 → 341
      PLN02153; epithiospecifier protein
      sd00038
      Location:78 → 119
      Kelch; KELCH repeat [structural motif]

    2. NM_001333628.1 → NP_001321531.1  epithiospecifier protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ARA7, A0A7G2E231

    3. NM_180632.2 → NP_850963.1  epithiospecifier protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850963.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RY71
      Conserved Domains (4) summary
      PLN02153
      Location:1 → 261
      PLN02153; epithiospecifier protein
      sd00038
      Location:1 → 39
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:1 → 39
      Kelch_1; Kelch motif
      pfam13964
      Location:47 → 97
      Kelch_6; Kelch motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RY71.2

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