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    RASA2 RAS p21 protein activator 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715074, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RASA2provided by VGNC
    Official Full Name
    RAS p21 protein activator 2provided by VGNC
    Primary source
    VGNC:VGNC:76668
    See related
    Ensembl:ENSMMUG00000009418
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RASA2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (43621957..43746628)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (160294601..160419781, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 38 Neighboring gene uncharacterized LOC114676258 Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene 14-3-3 protein theta pseudogene Neighboring gene uncharacterized LOC114676259 Neighboring gene ring finger protein 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras GTPase-activating protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      43621957..43746628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001112747.4 → XP_001112747.2  ras GTPase-activating protein 2 isoform X2

      UniProtKB/TrEMBL
      H9F9D7
      Conserved Domains (7) summary
      smart00107
      Location:708 → 743
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:172 → 314
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd08401
      Location:39 → 159
      C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
      smart00323
      Location:301 → 642
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13370
      Location:590 → 723
      PH_GAP1m_mammal-like; GTPase activating protein 1 m pleckstrin homology (PH) domain
      pfam00169
      Location:607 → 706
      PH; PH domain
      cl02569
      Location:323 → 593
      RasGAP; Ras GTPase Activating Domain

    2. XM_001112722.4 → XP_001112722.1  ras GTPase-activating protein 2 isoform X1

      UniProtKB/TrEMBL
      H9F9D7
      Conserved Domains (7) summary
      smart00107
      Location:711 → 746
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:172 → 314
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd08401
      Location:39 → 159
      C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
      smart00323
      Location:301 → 642
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13370
      Location:590 → 726
      PH_GAP1m_mammal-like; GTPase activating protein 1 m pleckstrin homology (PH) domain
      pfam00169
      Location:607 → 709
      PH; PH domain
      cl02569
      Location:323 → 593
      RasGAP; Ras GTPase Activating Domain

    3. XM_015131999.2 → XP_014987485.1  ras GTPase-activating protein 2 isoform X3

      UniProtKB/TrEMBL
      F6X9K0, H9F9D7, H9ZBX8
      Related
      ENSMMUP00000012325.4, ENSMMUT00000013151.4
      Conserved Domains (7) summary
      smart00107
      Location:707 → 742
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:172 → 314
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd08401
      Location:39 → 159
      C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
      smart00323
      Location:301 → 642
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13370
      Location:590 → 722
      PH_GAP1m_mammal-like; GTPase activating protein 1 m pleckstrin homology (PH) domain
      pfam00169
      Location:607 → 705
      PH; PH domain
      cl02569
      Location:323 → 593
      RasGAP; Ras GTPase Activating Domain
    Nucleotide Protein
    Heading Accession and Version

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