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    NF-YA1 nuclear factor Y, subunit A1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831124, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NF-YA1
    Official Full Name
    nuclear factor Y, subunit A1
    Primary source
    TAIR:AT5G12840
    Locus tag
    AT5G12840
    See related
    Araport:AT5G12840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''nuclear factor Y; ATHAP2A; AtNFYA1; EMB2220; EMBRYO DEFECTIVE 2220; HAP2A; NFYA1; nuclear factor Y; nuclear factor Y subunit A1; subunit A1; subunit A1''; T24H18.10; T24H18_10
    Summary
    Encodes a subunit of CCAAT-binding complex, binds to CCAAT box motif present in some plant promoter sequences. One of three members of this class (HAP2A, HAP2B, HAP2C), it is expressed in vegetative and reproductive tissues.
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    Genomic context

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    See NF-YA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (4050691..4053669, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene UvrABC system C protein, putative (DUF3411) Neighboring gene calmodulin-domain protein kinase 7 Neighboring gene CCCH-type zinc finger protein with ARM repeat domain-containing protein Neighboring gene dicarboxylate transporter 1 Neighboring gene myb domain protein 46

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NFYA1 is involved in regulation of postgermination growth arrest under salt stress in Arabidopsis. Li YJ, et al. PLoS One, 2013. PMID 23637805, Free PMC Article
    2. NUCLEAR FACTOR Y, Subunit A (NF-YA) Proteins Positively Regulate Flowering and Act Through FLOWERING LOCUS T. Siriwardana CL, et al. PLoS Genet, 2016 Dec. PMID 27977687, Free PMC Article
    3. Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis. Li X, et al. Cell Rep, 2024 Mar 26. PMID 38386555
    4. Arabidopsis transcription factor genes NF-YA1, 5, 6, and 9 play redundant roles in male gametogenesis, embryogenesis, and seed development. Mu J, et al. Mol Plant, 2013 Jan. PMID 22933713
    5. Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis. Edwards D, et al. Plant Physiol, 1998 Jul. PMID 9662544, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis.
      Title: Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis.
    2. Here we provide strong support, in the form of genetic and biochemical analyses, that NF-YA, in complex with NF-YB/NF-YC proteins, can directly bind the distal CCAAT box in the FT promoter and are positive regulators of flowering in an FT-dependent manner.
      Title: NUCLEAR FACTOR Y, Subunit A (NF-YA) Proteins Positively Regulate Flowering and Act Through FLOWERING LOCUS T.
    3. these results provide evidence that NF-YA1, 5, 6, and 9 play redundant roles in male gametophyte development, embryogenesis, seed development, and post-germinative growth.
      Title: Arabidopsis transcription factor genes NF-YA1, 5, 6, and 9 play redundant roles in male gametogenesis, embryogenesis, and seed development.
    4. NFYA1 is involved in regulation of postgermination growth arrest under salt stress in Arabidopsis.
      Title: NFYA1 is involved in regulation of postgermination growth arrest under salt stress in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001343248.1
    NM_121287.4
    NM_180480.3
    NM_203044.4
    NM_203045.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within microgametogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within somatic embryogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCAAT-binding factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nuclear factor Y, subunit A1
    NP_001318552.1
    • ''nuclear factor Y, subunit A1'' (NF-YA1); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289), CCAAT-binding factor, conserved site (InterPro:IPR018362); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A9 (TAIR:AT3G20910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_850811.1
    • ''nuclear factor Y, subunit A1'' (NF-YA1); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289), CCAAT-binding factor, conserved site (InterPro:IPR018362); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A9 (TAIR:AT3G20910.1); Has 687 Blast hits to 687 proteins in 162 species: Archae - 0; Bacteria - 0; Metazoa - 144; Fungi - 133; Plants - 381; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).
    NP_974773.1
    • ''nuclear factor Y, subunit A1'' (NF-YA1); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289), CCAAT-binding factor, conserved site (InterPro:IPR018362); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A9 (TAIR:AT3G20910.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974774.1
    • ''nuclear factor Y, subunit A1'' (NF-YA1); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289), CCAAT-binding factor, conserved site (InterPro:IPR018362); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A9 (TAIR:AT3G20910.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4050691..4053669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180480.3 → NP_850811.1  nuclear factor Y, subunit A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850811.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y5T6, A0A7G2FA58, B9DGV8
      Conserved Domains (1) summary
      smart00521
      Location:168 → 229
      CBF; CCAAT-Binding transcription Factor

    2. NM_203044.4 → NP_974773.1  nuclear factor Y, subunit A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974773.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23630, Q9LXV5
      UniProtKB/TrEMBL
      A0A5S9Y5T6, A0A654G0N9, Q1ECD3
      Conserved Domains (1) summary
      smart00521
      Location:169 → 230
      CBF; CCAAT-Binding transcription Factor

    3. NM_001343248.1 → NP_001318552.1  nuclear factor Y, subunit A1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23630, Q9LXV5
      UniProtKB/TrEMBL
      A0A5S9Y5T6, A0A654G0N9, Q1ECD3
      Conserved Domains (1) summary
      smart00521
      Location:169 → 230
      CBF; CCAAT-Binding transcription Factor

    4. NM_203045.2 → NP_974774.1  nuclear factor Y, subunit A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974774.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y5T6, A0A7G2FA58, B9DGV8
      Conserved Domains (1) summary
      smart00521
      Location:168 → 229
      CBF; CCAAT-Binding transcription Factor

    5. NM_121287.4 → NP_568282.1  nuclear factor Y, subunit A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568282.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23630, Q9LXV5
      UniProtKB/TrEMBL
      A0A5S9Y5T6, A0A654G0N9, Q1ECD3
      Conserved Domains (1) summary
      smart00521
      Location:169 → 230
      CBF; CCAAT-Binding transcription Factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LXV5.1

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