U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    ESPN espin [ Gallus gallus (chicken) ]

    Gene ID: 395461, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    ESPNprovided by CGNC
    Full Name
    espinprovided by CGNC
    Primary source
    CGNC:408
    See related
    Ensembl:ENSGALG00010019076
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ESPN in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (595115..607161, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (626754..638795, complement)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and RhoGEF domain containing G5 Neighboring gene uncharacterized LOC121107363 Neighboring gene TNF receptor superfamily member 25 Neighboring gene hes family bHLH transcription factor 2 Neighboring gene acyl-CoA thioesterase 7

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins. Zheng L, et al. Cell, 2000 Aug 4. PMID 10975527, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    espin

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      595115..607161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025142716.3 → XP_024998484.1  espin isoform X5

      Related
      ENSGALP00010027523.1, ENSGALT00010046187.1
      Conserved Domains (4) summary
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:8 → 55
      Ank_4; Ankyrin repeats (many copies)
      pfam02205
      Location:615 → 640
      WH2; WH2 motif
      pfam12796
      Location:176 → 268
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_015296966.4 → XP_015152452.1  espin isoform X4

      Conserved Domains (4) summary
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:8 → 55
      Ank_4; Ankyrin repeats (many copies)
      pfam02205
      Location:624 → 649
      WH2; WH2 motif
      pfam12796
      Location:176 → 268
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_015296965.4 → XP_015152451.1  espin isoform X3

      Conserved Domains (5) summary
      cd00204
      Location:167 → 292
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam02205
      Location:570 → 595
      WH2; WH2 motif
      pfam12796
      Location:176 → 302
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:72 → 124
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    4. XM_015296964.4 → XP_015152450.1  espin isoform X2

      Conserved Domains (5) summary
      cd00204
      Location:167 → 292
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam02205
      Location:615 → 640
      WH2; WH2 motif
      pfam12796
      Location:176 → 302
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:72 → 124
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    5. XM_015296963.4 → XP_015152449.1  espin isoform X1

      Conserved Domains (5) summary
      cd00204
      Location:167 → 292
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam02205
      Location:624 → 649
      WH2; WH2 motif
      pfam12796
      Location:176 → 302
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:72 → 124
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    6. XM_040651242.2 → XP_040507176.1  espin isoform X7

    7. XM_040651241.2 → XP_040507175.1  espin isoform X6

    8. XM_040651243.2 → XP_040507177.1  espin isoform X8

    RNA

    1. XR_005841382.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      626754..638795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040688869.2 → XP_040544803.1  espin isoform X5

      Conserved Domains (4) summary
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:8 → 55
      Ank_4; Ankyrin repeats (many copies)
      pfam02205
      Location:615 → 640
      WH2; WH2 motif
      pfam12796
      Location:176 → 268
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_040688867.2 → XP_040544801.1  espin isoform X4

      Conserved Domains (4) summary
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:8 → 55
      Ank_4; Ankyrin repeats (many copies)
      pfam02205
      Location:624 → 649
      WH2; WH2 motif
      pfam12796
      Location:176 → 268
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_040688866.2 → XP_040544800.1  espin isoform X3

      Conserved Domains (3) summary
      PHA02874
      Location:72 → 312
      PHA02874; ankyrin repeat protein; Provisional
      COG0666
      Location:6 → 128
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    4. XM_040688865.2 → XP_040544799.1  espin isoform X2

      Conserved Domains (3) summary
      PHA02874
      Location:72 → 312
      PHA02874; ankyrin repeat protein; Provisional
      COG0666
      Location:6 → 128
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    5. XM_040688864.2 → XP_040544798.1  espin isoform X1

      Conserved Domains (3) summary
      PHA02874
      Location:72 → 312
      PHA02874; ankyrin repeat protein; Provisional
      COG0666
      Location:6 → 128
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:172 → 203
      ANK; ANK repeat [structural motif]

    6. XM_040688871.2 → XP_040544805.1  espin isoform X7

    7. XM_040688870.2 → XP_040544804.1  espin isoform X6

    8. XM_040688872.2 → XP_040544806.1  espin isoform X8

    RNA

    1. XR_005855555.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials