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    BtbVII BTB-protein-VII [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BtbVIIprovided by FlyBase
    Official Full Name
    BTB-protein-VIIprovided by FlyBase
    Primary source
    FLYBASE:FBgn0263108
    Locus tag
    Dmel_CG43365
    See related
    AllianceGenome:FB:FBgn0263108
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH07729; BTB-VII; BTBVII; CG11494; CG14956; CG43365; Dmel\CG43365
    Old locus tag
    Dmel_CG11494; Dmel_CG14956
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; embryonic/larval midgut primordium; ganglia; and larval nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See BtbVII in Genome Data Viewer
    Location:
    63B7-63B7; 3-6 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3148646..3158408)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3148646..3158408)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene ALG2, alpha-1,3/1,6-mannosyltransferase Neighboring gene Ubiquitin specific protease 5 Neighboring gene NADH dehydrogenase (ubiquinone) 30 kDa subunit Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Zollman S, et al. Proc Natl Acad Sci U S A, 1994 Oct 25. PMID 7938017, Free PMC Article
    2. Modulation of Global Gene Expression by Aneuploidy and CNV of Dosage Sensitive Regulatory Genes. Zhang S, et al. Genes (Basel), 2021 Oct 12. PMID 34681000, Free PMC Article
    3. Parallel on-chip gene synthesis and application to optimization of protein expression. Quan J, et al. Nat Biotechnol, 2011 May. PMID 21516083
    4. The deubiquitinase Leon/USP5 regulates ubiquitin homeostasis during Drosophila development. Wang CH, et al. Biochem Biophys Res Commun, 2014 Sep 26. PMID 25152394
    5. Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity. Post S, et al. Front Endocrinol (Lausanne), 2018. PMID 29892262, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BTB-protein-VII
    Names
    BTB protein VII
    BtbVII-PA
    BtbVII-PB
    BtbVII-PD
    BtbVII-PE
    BtbVII-PF
    BtbVII-PG
    BtbVII-PH
    BtbVII-PI
    CG43365-PA
    CG43365-PB
    CG43365-PD
    CG43365-PE
    CG43365-PF
    CG43365-PG
    CG43365-PH
    CG43365-PI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3148646..3158408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139517.3 → NP_647774.2  BTB-protein-VII, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647774.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZU5
      Conserved Domains (2) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain

    2. NM_001274427.2 → NP_001261356.1  BTB-protein-VII, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261356.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PH51
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:566 → 611
      HTH_psq; helix-turn-helix, Psq domain

    3. NM_001274426.1 → NP_001261355.1  BTB-protein-VII, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261355.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE48
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:567 → 612
      HTH_psq; helix-turn-helix, Psq domain

    4. NM_001259661.2 → NP_001246590.1  BTB-protein-VII, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246590.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960S0
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:562 → 607
      HTH_psq; helix-turn-helix, Psq domain

    5. NM_001144408.3 → NP_001137880.2  BTB-protein-VII, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137880.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z045
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:562 → 607
      HTH_psq; helix-turn-helix, Psq domain

    6. NM_079172.4 → NP_523896.2  BTB-protein-VII, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523896.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960S0
      Related
      FBpp0298303
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:562 → 607
      HTH_psq; helix-turn-helix, Psq domain

    7. NM_001259662.1 → NP_001246591.1  BTB-protein-VII, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246591.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960S0
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:562 → 607
      HTH_psq; helix-turn-helix, Psq domain

    8. NM_167990.3 → NP_728814.1  BTB-protein-VII, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728814.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960S0
      Related
      FBpp0298306
      Conserved Domains (3) summary
      smart00225
      Location:32 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:24 → 117
      BTB; BTB/POZ domain
      pfam05225
      Location:562 → 607
      HTH_psq; helix-turn-helix, Psq domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z045 B7Z045
    M9PE48 M9PE48
    M9PH51 M9PH51
    Q8SXC5 Q8SXC5
    Q960S0 Q960S0
    Q9VZU5 Q9VZU5
    Q9VZU6 Q9VZU6

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