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    Vmn2r122 vomeronasal 2, receptor, 122 [ Mus musculus (house mouse) ]

    Gene ID: 22308, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vmn2r122provided by MGI
    Official Full Name
    vomeronasal 2, receptor, 122provided by MGI
    Primary source
    MGI:MGI:1316661
    See related
    AllianceGenome:MGI:1316661
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    V2r2; V2r12; Vmn2r-ps158
    Summary
    Is expressed in dorsal root ganglion; eye; neural tube; and nose. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Vmn2r122 in Genome Data Viewer
    Location:
    4 E2; 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (156554341..156562726)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 Unlocalized Scaffold NT_187052.1 (3536..11935)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54277 Neighboring gene predicted gene, 54279 Neighboring gene predicted gene, 53275 Neighboring gene vomeronasal 2, receptor 129

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FGF signalling controls expression of vomeronasal receptors during embryogenesis. Lioubinski O, et al. Mech Dev, 2006 Jan. PMID 16326081
    2. A new multigene family of putative pheromone receptors. Ryba NJ, et al. Neuron, 1997 Aug. PMID 9292726
    3. A candidate taste receptor gene near a sweet taste locus. Montmayeur JP, et al. Nat Neurosci, 2001 May. PMID 11319557
    4. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
    5. Positional cloning of the mouse saccharin preference (Sac) locus. Bachmanov AA, et al. Chem Senses, 2001 Sep. PMID 11555487, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor, 122
    Names
    vomeronasal 2, receptor, 12
    vomeronasal 2, receptor, 2
    vomeronasal organ family 2, receptor, 12
    vomeronasal organ family 2, receptor, 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001385246.2 → NP_001372175.2  vomeronasal 2, receptor, 122 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (3) summary
      cd15283
      Location:582 → 832
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:508 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. NM_001385247.2 → NP_001372176.2  vomeronasal 2, receptor, 122 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (3) summary
      cd15283
      Location:581 → 831
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:508 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    3. NM_001385250.2 → NP_001372179.1  vomeronasal 2, receptor, 122 isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      Conserved Domains (1) summary
      cl10011
      Location:46 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    4. NM_001385252.2 → NP_001372181.1  vomeronasal 2, receptor, 122 isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      Conserved Domains (1) summary
      cl10011
      Location:46 → 432
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    5. NM_009488.4 → NP_033514.3  vomeronasal 2, receptor, 122 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (2) summary
      cd15283
      Location:506 → 756
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cl10011
      Location:46 → 463
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    6. NM_009492.4 → NP_033518.3  vomeronasal 2, receptor, 122 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC245278
      UniProtKB/TrEMBL
      A0A3Q4EIC8, O35190
      Conserved Domains (2) summary
      cd15283
      Location:541 → 791
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      156554341..156562726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163979.1 → XP_036019872.1  vomeronasal 2, receptor, 122 isoform X1

      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (3) summary
      cd15283
      Location:583 → 833
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:510 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
    Nucleotide Protein Strain
    Heading Accession and Version

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