CDC20.2 Transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CDC20.2
Official Full Name: Transducin family protein / WD-40 repeat family protein
Primary source: TAIR:AT4G33260
Locus tag: AT4G33260
See related: Araport:AT4G33260
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtCDC20.2; cell division cycle 20.2; F17M5.20; F17M5_20
Summary: Encodes a CDC20 protein that interacts with APC subunits, components of the mitochondrial checkpoint complex and mitotic cyclin substrates and is indispensable for normal plant development and fertility.
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Genomic context

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See CDC20.2 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 5

Sequence:: Chromosome: 4; NC_003075.7 (16041006..16043549, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

conserved CDC20 functions could be assigned for AtCDC20.1 and AtCDC20.2
Title: Conserved CDC20 cell cycle functions are carried out by two of the five isoforms in Arabidopsis thaliana.
Studies indicate that the APC is composed of at least 11 subunits and associates with additional regulatory activators CDC20/CCS52 during mitosis and interphase cycles.
Title: Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001203971.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables anaphase-promoting complex binding	IEA Inferred from Electronic Annotation more info
enables kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables ubiquitin-protein transferase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of mitotic checkpoint complex	IPI Inferred from Physical Interaction more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Transducin family protein / WD-40 repeat family protein

NP_001190900.1

CDC20.2; FUNCTIONS IN: signal transducer activity; INVOLVED IN: signal transduction; LOCATED IN: heterotrimeric G-protein complex; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT4G33270.1).

NP_195052.1

CDC20.2; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat, conserved site (InterPro:IPR019775), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT4G33270.1); Has 49557 Blast hits to 24743 proteins in 707 species: Archae - 58; Bacteria - 7555; Metazoa - 19332; Fungi - 10955; Plants - 5960; Viruses - 0; Other Eukaryotes - 5697 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16041006..16043549 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119480.4 → NP_195052.1 Transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195052.1

Status: REVIEWED

UniProtKB/Swiss-Prot

F4JW04, Q9S7I8

UniProtKB/TrEMBL

A0A5S9XY62

Conserved Domains (3) summary

COG2319
Location:139 → 425

WD40; WD40 repeat [General function prediction only]

cd00200
Location:149 → 420

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:175 → 212

7WD40; WD40 repeat [structural motif]
NM_001203971.1 → NP_001190900.1 Transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190900.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9XY62

Conserved Domains (3) summary

COG2319
Location:139 → 425

WD40; WD40 repeat [General function prediction only]

cd00200
Location:149 → 416

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:175 → 212

7WD40; WD40 repeat [structural motif]