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    zhit-1 HIT-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183878, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zhit-1
    Official Full Name
    HIT-type domain-containing protein
    Primary source
    WormBase:WBGene00016992
    Locus tag
    CELE_CD4.7
    See related
    AllianceGenome:WB:WBGene00016992
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nucleosome binding activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of Swr1 complex. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zhit-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (5595653..5596551, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene VPS37 C-terminal domain-containing protein Neighboring gene Small ribosomal subunit protein uS10 domain-containing protein Neighboring gene Deoxyribonuclease TATDN1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SPK domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. Cui M, et al. PLoS Genet, 2006 May. PMID 16710447, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HIT-type domain-containing protein
    NP_001122894.1
    • Confirmed by transcript evidence
    NP_504477.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5595653..5596551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129422.3 → NP_001122894.1  HIT-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122894.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9D699
      Conserved Domains (2) summary
      pfam04438
      Location:154 → 180
      zf-HIT; HIT zinc finger
      cl02154
      Location:100 → 175
      YL1_C; YL1 nuclear protein C-terminal domain

    2. NM_072076.8 → NP_504477.2  HIT-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504477.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44161
      Conserved Domains (1) summary
      cl02154
      Location:29 → 101
      YL1_C; YL1 nuclear protein C-terminal domain
    Nucleotide Protein
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