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    hum-5 Unconventional myosin-Id [ Caenorhabditis elegans ]

    Gene ID: 175521, updated on 9-Dec-2024

    Summary

    Official Symbol
    hum-5
    Official Full Name
    Unconventional myosin-Id
    Primary source
    WormBase:WBGene00002038
    Locus tag
    CELE_T02C12.1
    See related
    AllianceGenome:WB:WBGene00002038
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization; actin filament-based movement; and endocytosis. Predicted to be part of myosin complex. Predicted to be active in several cellular components, including actin cytoskeleton; microvillus; and plasma membrane. Is expressed in several structures, including excretory cell; pharyngeal-intestinal valve; pharynx; reproductive system; and tail. Orthologous to several human genes including MYO1G (myosin IG). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See hum-5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    16
    Sequence:
    Chromosome: III; NC_003281.10 (4029115..4036834, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene General transcription factor 3C polypeptide 5 Neighboring gene AAI domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding  
    enables actin binding  
    enables actin filament binding  
    enables cytoskeletal motor activity  
    enables microfilament motor activity  
    Process Evidence Code Pubs
    involved_in actin filament organization  
    involved_in actin filament-based movement  
    involved_in endocytosis  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton  
    is_active_in cytoplasm  
    is_active_in microvillus  
    part_of myosin complex  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    Unconventional myosin-Id
    NP_497809.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4029115..4036834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065408.8NP_497809.1  Unconventional myosin-Id [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497809.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECZ0
      Conserved Domains (3) summary
      smart00242
      Location:6699
      MYSc; Myosin. Large ATPases
      cd01378
      Location:26687
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:808986
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding
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