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    H12I13.1 Ubiquitin carboxyl-terminal hydrolase [ Caenorhabditis elegans ]

    Gene ID: 186732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    H12I13.1
    Official Full Name
    Ubiquitin carboxyl-terminal hydrolase
    Primary source
    WormBase:WBGene00019190
    Locus tag
    CELE_H12I13.1
    See related
    AllianceGenome:WB:WBGene00019190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity; cysteine-type deubiquitinase activity; and protein kinase activity. Predicted to be involved in protein deubiquitination; protein phosphorylation; and proteolysis. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See H12I13.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (6061977..6067166, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Zf-AD domain-containing protein Neighboring gene pseudo Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin carboxyl-terminal hydrolase
    NP_001335513.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6061977..6067166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001348635.1 → NP_001335513.1  Ubiquitin carboxyl-terminal hydrolase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N5M9
      Conserved Domains (3) summary
      pfam00443
      Location:78 → 369
      UCH; Ubiquitin carboxyl-terminal hydrolase
      cl11619
      Location:473 → 589
      SPK; Domain of unknown function (DUF545)
      cl21453
      Location:673 → 854
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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