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    CACNA1G calcium voltage-gated channel subunit alpha1 G [ Bos taurus (domestic cattle) ]

    Gene ID: 282411, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CACNA1Gprovided by VGNC
    Official Full Name
    calcium voltage-gated channel subunit alpha1 Gprovided by VGNC
    Primary source
    VGNC:VGNC:26677
    See related
    BGD:BT11773; Ensembl:ENSBTAG00000009835
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CACNA1G in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (36102401..36164794, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 40 Neighboring gene ATP binding cassette subfamily C member 3 Neighboring gene uncharacterized LOC101902385 Neighboring gene spermatogenesis associated 20 Neighboring gene epsin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. alpha1H T-type Ca2+ channel is the predominant subtype expressed in bovine and rat zona glomerulosa. Schrier AD, et al. Am J Physiol Cell Physiol, 2001 Feb. PMID 11208520
    2. Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture. Walsh CP, et al. J Biol Chem, 2009 Aug 14. PMID 19520861, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CaV3.1 structural analysis and comparison to CaV1.2 channel
      Title: Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables low voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion import IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of calcium ion-dependent exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    voltage-dependent T-type calcium channel subunit alpha-1G
    Names
    calcium channel, voltage-dependent, alpha 1G subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193140.3 → NP_001180069.2  voltage-dependent T-type calcium channel subunit alpha-1G

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000019
      UniProtKB/TrEMBL
      A0AAA9TYV9, F1MR37
      Related
      ENSBTAP00000012985.6, ENSBTAT00000012985.7
      Conserved Domains (3) summary
      PRK11633
      Location:534 → 616
      PRK11633; cell division protein DedD; Provisional
      pfam00520
      Location:740 → 969
      Ion_trans; Ion transport protein
      cl28033
      Location:2094 → 2361
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36102401..36164794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220488.5 → XP_005220545.2  voltage-dependent T-type calcium channel subunit alpha-1G isoform X18

      UniProtKB/TrEMBL
      A0A3Q1MA91, A0AAA9TYV9
      Related
      ENSBTAP00000067514.2, ENSBTAT00000066790.2
      Conserved Domains (3) summary
      PRK11633
      Location:534 → 616
      PRK11633; cell division protein DedD; Provisional
      pfam00520
      Location:740 → 973
      Ion_trans; Ion transport protein
      cl28033
      Location:2060 → 2327
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. XM_059877742.1 → XP_059733725.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X19

      UniProtKB/TrEMBL
      A0AAA9TYV9

    3. XM_015458771.3 → XP_015314257.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X1

      UniProtKB/TrEMBL
      A0AAA9TYV9
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 969
      Ion_trans; Ion transport protein

    4. XM_005220487.5 → XP_005220544.2  voltage-dependent T-type calcium channel subunit alpha-1G isoform X17

      UniProtKB/TrEMBL
      A0A3Q1M721, A0AAA9TYV9
      Related
      ENSBTAP00000066142.2, ENSBTAT00000079905.2
      Conserved Domains (3) summary
      PRK11633
      Location:534 → 616
      PRK11633; cell division protein DedD; Provisional
      pfam00520
      Location:740 → 969
      Ion_trans; Ion transport protein
      cl28033
      Location:2083 → 2350
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    5. XM_005220494.5 → XP_005220551.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X5

      See identical proteins and their annotated locations for XP_005220551.1

      UniProtKB/TrEMBL
      A0A3Q1LTV8, A0AAA9TYV9
      Related
      ENSBTAP00000063920.2, ENSBTAT00000084730.2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 973
      Ion_trans; Ion transport protein

    6. XM_059877736.1 → XP_059733719.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X6

      UniProtKB/TrEMBL
      A0AAA9TYV9

    7. XM_059877735.1 → XP_059733718.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X3

      UniProtKB/TrEMBL
      A0AAA9TYV9

    8. XM_024979634.2 → XP_024835402.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (3) summary
      PRK11633
      Location:534 → 616
      PRK11633; cell division protein DedD; Provisional
      pfam00520
      Location:740 → 969
      Ion_trans; Ion transport protein
      cl28033
      Location:2024 → 2291
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    9. XM_059877734.1 → XP_059733717.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X2

      UniProtKB/TrEMBL
      A0AAA9TYV9

    10. XM_005220507.5 → XP_005220564.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X12

      See identical proteins and their annotated locations for XP_005220564.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 973
      Ion_trans; Ion transport protein

    11. XM_005220502.5 → XP_005220559.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X10

      See identical proteins and their annotated locations for XP_005220559.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 973
      Ion_trans; Ion transport protein

    12. XM_005220505.5 → XP_005220562.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X11

      See identical proteins and their annotated locations for XP_005220562.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 973
      Ion_trans; Ion transport protein

    13. XM_005220501.5 → XP_005220558.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X9

      See identical proteins and their annotated locations for XP_005220558.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 969
      Ion_trans; Ion transport protein

    14. XM_005220497.5 → XP_005220554.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X7

      See identical proteins and their annotated locations for XP_005220554.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Related
      ENSBTAP00000063254.2, ENSBTAT00000075989.2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 969
      Ion_trans; Ion transport protein

    15. XM_005220499.5 → XP_005220556.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X8

      See identical proteins and their annotated locations for XP_005220556.1

      UniProtKB/TrEMBL
      A0A3Q1M4R2
      Conserved Domains (1) summary
      pfam00520
      Location:758 → 969
      Ion_trans; Ion transport protein

    16. XM_059877737.1 → XP_059733720.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X13

      UniProtKB/TrEMBL
      A0AAA9TYV9

    17. XM_059877738.1 → XP_059733721.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X14

    18. XM_059877741.1 → XP_059733724.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X16

    19. XM_059877739.1 → XP_059733722.1  voltage-dependent T-type calcium channel subunit alpha-1G isoform X15

    Nucleotide Protein Strain
    Heading Accession and Version

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