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    ITGA7 integrin subunit alpha 7 [ Bos taurus (domestic cattle) ]

    Gene ID: 506953, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ITGA7provided by VGNC
    Official Full Name
    integrin subunit alpha 7provided by VGNC
    Primary source
    VGNC:VGNC:56212
    See related
    BGD:BT30331; Ensembl:ENSBTAG00000012897
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ITGA7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (57547850..57572012)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 5 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 1 Neighboring gene thiol methyltransferase 1B Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene olfactory receptor family 10 subfamily P member 25

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leukocyte migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-7
    Names
    integrin, alpha 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191305.1 → NP_001178234.1  integrin alpha-7

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000005
      UniProtKB/TrEMBL
      A0AAA9SLM4, E1BGA0
      Related
      ENSBTAP00000017145.6, ENSBTAT00000017145.6
      Conserved Domains (2) summary
      smart00191
      Location:382 → 433
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:475 → 969
      Integrin_alpha2; Integrin alpha

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      57547850..57572012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886211.1 → XP_059742194.1  integrin alpha-7 isoform X6

    2. XM_024991498.2 → XP_024847266.1  integrin alpha-7 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SLM4
      Related
      ENSBTAP00000083564.1, ENSBTAT00000106790.1
      Conserved Domains (2) summary
      smart00191
      Location:382 → 433
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:475 → 966
      Integrin_alpha2; Integrin alpha

    3. XM_024991497.2 → XP_024847265.1  integrin alpha-7 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SLM4
      Conserved Domains (3) summary
      smart00191
      Location:404 → 455
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:497 → 988
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:315 → 365
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    4. XM_024991496.2 → XP_024847264.1  integrin alpha-7 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SLM4
      Conserved Domains (3) summary
      smart00191
      Location:404 → 455
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:497 → 988
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:315 → 365
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    5. XM_024991499.2 → XP_024847267.1  integrin alpha-7 isoform X2

      UniProtKB/TrEMBL
      A0AAA9RS90, A0AAA9SLM4
      Related
      ENSBTAP00000075342.1, ENSBTAT00000133099.1
      Conserved Domains (3) summary
      smart00191
      Location:378 → 429
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:471 → 962
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:289 → 339
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    6. XM_059886212.1 → XP_059742195.1  integrin alpha-7 isoform X8

      UniProtKB/TrEMBL
      A0AAA9SLM4, A0AAA9TPF9
      Related
      ENSBTAP00000098905.1, ENSBTAT00000119011.1

    7. XM_024991501.2 → XP_024847269.1  integrin alpha-7 isoform X7

      Conserved Domains (3) summary
      smart00191
      Location:217 → 268
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:310 → 801
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:128 → 178
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    8. XM_024991500.2 → XP_024847268.2  integrin alpha-7 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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