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    Tsp42Ep Tetraspanin 42Ep [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35626, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tsp42Epprovided by FlyBase
    Official Full Name
    Tetraspanin 42Epprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033137
    Locus tag
    Dmel_CG4471
    See related
    AllianceGenome:FB:FBgn0033137
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4471; Dm.Tsp42Ep; Dmel\CG4471
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tsp42Ep in Genome Data Viewer
    Location:
    42E7-42E7; 2-55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7054405..7057548, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2941910..2945053, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene late bloomer Neighboring gene Tetraspanin 42En Neighboring gene Tetraspanin 42Eo Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 3 Neighboring gene Tetraspanin 42Eq

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GATA factors participate in tissue-specific immune responses in Drosophila larvae. Senger K, et al. Proc Natl Acad Sci U S A, 2006 Oct 24. PMID 17032752, Free PMC Article
    2. A mucin-type O-glycosyltransferase modulates cell adhesion during Drosophila development. Zhang L, et al. J Biol Chem, 2008 Dec 5. PMID 18835818, Free PMC Article
    3. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
    4. Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma. Jeibmann A, et al. J Neurooncol, 2015 Sep. PMID 26224160
    5. Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Fradkin LG, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370414, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tetraspanin 42Ep
    Names
    CG4471-PA
    CG4471-PB
    Tsp42Ep-PA
    Tsp42Ep-PB
    tetraspanin 42E

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7054405..7057548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273830.2 → NP_001260759.1  tetraspanin 42Ep, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260759.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6U7, Q8SY31
      Conserved Domains (2) summary
      cd03127
      Location:91 → 183
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:51 → 213
      Tetraspannin; Tetraspanin family

    2. NM_078918.4 → NP_523642.1  tetraspanin 42Ep, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523642.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6U7, Q8SY31
      Related
      FBpp0088131
      Conserved Domains (2) summary
      cd03127
      Location:91 → 183
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:51 → 213
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z6U7 A1Z6U7
    Q8SY31 Q8SY31

    Gene LinkOut

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