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    Slc45-1 Solute carrier family 45 member 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39055, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc45-1provided by FlyBase
    Official Full Name
    Solute carrier family 45 member 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0035968
    Locus tag
    Dmel_CG4484
    See related
    AllianceGenome:FB:FBgn0035968
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4484; Dmel\CG4484; scrt
    Summary
    Enables sucrose transmembrane transporter activity. Involved in sucrose transport. Located in apical part of cell and cytoplasmic vesicle. Is expressed in adult head; embryonic/larval hindgut; follicle cell; and organism. Human ortholog(s) of this gene implicated in oculocutaneous albinism type IV and pigmentation disease. Orthologous to human SLC45A2 (solute carrier family 45 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Slc45-1 in Genome Data Viewer
    Location:
    67A3-67A3; 3-28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9203065..9208853, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9196165..9201953, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene nervous wreck Neighboring gene mir-4940 stem loop Neighboring gene Resistant to dieldrin Neighboring gene long non-coding RNA:CR45408 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in apical part of cell PubMed 
    located_in cytoplasmic vesicle PubMed 
    is_active_in membrane  

    General protein information

    Preferred Names
    solute carrier family 45 member 1
    Names
    CG4484-PA
    CG4484-PB
    CG4484-PC
    CG4484-PD
    Slc45 ortholog 1
    Slc45-1-PA
    Slc45-1-PB
    Slc45-1-PC
    Slc45-1-PD
    sucrose transporter

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9203065..9208853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140035.2 → NP_648292.1  solute carrier family 45 member 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648292.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSV1
      Related
      FBpp0076231
      Conserved Domains (2) summary
      cd06174
      Location:444 → 597
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR01301
      Location:49 → 568
      GPH_sucrose; GPH family sucrose/H+ symporter
    2. NM_001274689.1 → NP_001261618.1  solute carrier family 45 member 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261618.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSV1
      Conserved Domains (2) summary
      cd06174
      Location:444 → 597
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR01301
      Location:49 → 568
      GPH_sucrose; GPH family sucrose/H+ symporter
    3. NM_001274690.1 → NP_001261619.1  solute carrier family 45 member 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261619.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSV1
      Conserved Domains (2) summary
      cd06174
      Location:444 → 597
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR01301
      Location:49 → 568
      GPH_sucrose; GPH family sucrose/H+ symporter
    4. NM_001274691.1 → NP_001261620.1  solute carrier family 45 member 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261620.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSV1
      Conserved Domains (2) summary
      cd06174
      Location:444 → 597
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR01301
      Location:49 → 568
      GPH_sucrose; GPH family sucrose/H+ symporter
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