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    swp-1 Protein SWAP;SURP motif domain-containing protein;Suppressor of white apricot N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175795, updated on 9-Dec-2024

    Summary

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    Official Symbol
    swp-1
    Official Full Name
    Protein SWAP;SURP motif domain-containing protein;Suppressor of white apricot N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00006359
    Locus tag
    CELE_B0336.9
    See related
    AllianceGenome:WB:WBGene00006359
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Orthologous to human SFSWAP (splicing factor SWAP). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See swp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (5702206..5705464, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transcription initiation factor IIA small chain homolog Neighboring gene THAP-type domain-containing protein Neighboring gene Ubiquitin-like protein atg-12 Neighboring gene RGS domain-containing protein;Regulator of G-protein signaling rgs-5 Neighboring gene Large ribosomal subunit protein uL14 Neighboring gene Major sperm protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SWAP pre-mRNA splicing regulators are a novel, ancient protein family sharing a highly conserved sequence motif with the prp21 family of constitutive splicing proteins. Spikes DA, et al. Nucleic Acids Res, 1994 Oct 25. PMID 7971282, Free PMC Article
    2. Alternative splicing and the steady-state ratios of mRNA isoforms generated by it are under strong stabilizing selection in Caenorhabditis elegans. Barberan-Soler S, et al. Mol Biol Evol, 2008 Nov. PMID 18718918, Free PMC Article
    3. High qualitative and quantitative conservation of alternative splicing in Caenorhabditis elegans and Caenorhabditis briggsae. Rukov JL, et al. Mol Biol Evol, 2007 Apr. PMID 17272679
    4. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    5. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA 5'-splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein SWAP;SURP motif domain-containing protein;Suppressor of white apricot N-terminal domain-containing protein
    NP_001021122.1
    • Confirmed by transcript evidence
    NP_001367326.1
    • Confirmed by transcript evidence
    NP_001379554.1
    • Confirmed by transcript evidence
    NP_001379555.1
    • Confirmed by transcript evidence
    NP_741149.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5702206..5705464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379724.2 → NP_001367326.1  Protein SWAP [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (2) summary
      smart00648
      Location:80 → 134
      SWAP; Suppressor-of-White-APricot splicing regulator
      pfam09750
      Location:1 → 44
      DRY_EERY; Alternative splicing regulator

    2. NM_171132.4 → NP_741149.1  Protein SWAP [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741149.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q10580, Q17484, Q8WQH0
      Conserved Domains (2) summary
      smart00648
      Location:164 → 218
      SWAP; Suppressor-of-White-APricot splicing regulator
      pfam09750
      Location:18 → 128
      DRY_EERY; Alternative splicing regulator

    3. NM_001392108.1 → NP_001379554.1  Suppressor of white apricot N-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KY77
      Conserved Domains (1) summary
      pfam09750
      Location:22 → 61
      DRY_EERY; Alternative splicing regulator

    4. NM_001025951.3 → NP_001021122.1  SURP motif domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021122.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MPQ0
      Conserved Domains (2) summary
      smart00648
      Location:168 → 222
      SWAP; Suppressor-of-White-APricot splicing regulator
      pfam09750
      Location:22 → 132
      DRY_EERY; Alternative splicing regulator

    5. NM_001392107.1 → NP_001379555.1  Suppressor of white apricot N-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KY78
      Conserved Domains (1) summary
      pfam09750
      Location:22 → 60
      DRY_EERY; Alternative splicing regulator
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q10580.1

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