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    VAC14 VAC14 component of PIKFYVE complex [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708741, updated on 17-Aug-2024

    Summary

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    Official Symbol
    VAC14provided by VGNC
    Official Full Name
    VAC14 component of PIKFYVE complexprovided by VGNC
    Primary source
    VGNC:VGNC:79506
    Locus tag
    EGK_12980
    See related
    Ensembl:ENSMMUG00000020421
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See VAC14 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (60698349..60813334)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (54942062..55057050, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene cap methyltransferase 2 Neighboring gene HYDIN axonemal central pair apparatus protein Neighboring gene U6atac minor spliceosomal RNA Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene MTSS I-BAR domain containing 2 Neighboring gene interleukin 34

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in phosphatidylinositol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of PAS complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein VAC14 homolog
    Names
    Tax1-binding protein 2
    Vac14, PIKFYVE complex component

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261476.1 → NP_001248405.1  protein VAC14 homolog

      See identical proteins and their annotated locations for NP_001248405.1

      Status: PROVISIONAL

      Source sequence(s)
      JU476344
      UniProtKB/TrEMBL
      A0A8J8XD54, F6RXT2, G7NQQ3, I0FT97
      Related
      ENSMMUP00000032326.1, ENSMMUT00000039240.3
      Conserved Domains (3) summary
      pfam11916
      Location:543 → 717
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      60698349..60813334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840527.1 → XP_028696360.1  protein VAC14 homolog isoform X7

      Conserved Domains (1) summary
      pfam11916
      Location:308 → 483
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding

    2. XM_028840521.1 → XP_028696354.1  protein VAC14 homolog isoform X2

      UniProtKB/TrEMBL
      I0FT97
      Conserved Domains (4) summary
      PRK07764
      Location:689 → 797
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:542 → 678
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    3. XM_015126507.2 → XP_014981993.1  protein VAC14 homolog isoform X6

      UniProtKB/TrEMBL
      I0FT97
      Related
      ENSMMUP00000073173.1, ENSMMUT00000083165.1
      Conserved Domains (3) summary
      pfam11916
      Location:543 → 678
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]

    4. XM_028840523.1 → XP_028696356.1  protein VAC14 homolog isoform X4

      Conserved Domains (3) summary
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:546 → 615
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    5. XM_028840520.1 → XP_028696353.1  protein VAC14 homolog isoform X1

      UniProtKB/TrEMBL
      I0FT97
      Conserved Domains (4) summary
      PRK07764
      Location:693 → 801
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:546 → 682
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    6. XM_028840522.1 → XP_028696355.1  protein VAC14 homolog isoform X3

      UniProtKB/TrEMBL
      I0FT97
      Conserved Domains (3) summary
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:546 → 721
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    7. XM_028840526.1 → XP_028696359.1  protein VAC14 homolog isoform X5

      UniProtKB/TrEMBL
      I0FT97
      Conserved Domains (3) summary
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:546 → 682
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    8. XM_028840524.1 → XP_028696357.1  protein VAC14 homolog isoform X4

      Conserved Domains (3) summary
      sd00044
      Location:94 → 122
      HEAT; HEAT repeat [structural motif]
      pfam11916
      Location:546 → 615
      Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
      pfam12755
      Location:67 → 163
      Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region

    RNA

    1. XR_003725286.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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