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    KANK2 KN motif and ankyrin repeat domains 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716191, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KANK2provided by VGNC
    Official Full Name
    KN motif and ankyrin repeat domains 2provided by VGNC
    Primary source
    VGNC:VGNC:73938
    See related
    Ensembl:ENSMMUG00000023251
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KANK2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (10924464..10960628, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (11186921..11222900, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor Neighboring gene uncharacterized LOC114674158 Neighboring gene SPC24 component of NDC80 kinetochore complex Neighboring gene dedicator of cytokinesis 6 Neighboring gene angiopoietin like 8 Neighboring gene tetraspanin 16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of intracellular estrogen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of vitamin D receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KN motif and ankyrin repeat domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      10924464..10960628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838717.1 → XP_028694550.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_015122927.2 → XP_014978413.2  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q686, F7E663, G7NL20
      Related
      ENSMMUP00000043552.2, ENSMMUT00000068339.2
      Conserved Domains (5) summary
      COG0666
      Location:651 → 806
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:666 → 698
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:743 → 828
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_015122929.2 → XP_014978415.2  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q686, F7E663, G7NL20
      Related
      ENSMMUP00000030597.4, ENSMMUT00000032699.4
      Conserved Domains (5) summary
      COG0666
      Location:651 → 806
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:666 → 698
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:743 → 828
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_028838720.1 → XP_028694553.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_028838716.1 → XP_028694549.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_028838719.1 → XP_028694552.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    7. XM_028838718.1 → XP_028694551.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    8. XM_028838715.1 → XP_028694548.1  KN motif and ankyrin repeat domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:659 → 814
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:674 → 706
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:751 → 836
      Ank_2; Ankyrin repeats (3 copies)

    9. XM_015122928.2 → XP_014978414.2  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q686, F7E663, G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:651 → 806
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:666 → 698
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:743 → 828
      Ank_2; Ankyrin repeats (3 copies)

    10. XM_015122925.2 → XP_014978411.2  KN motif and ankyrin repeat domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q686, F7E663, G7NL20
      Conserved Domains (5) summary
      COG0666
      Location:651 → 806
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      PTZ00108
      Location:189 → 305
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00045
      Location:666 → 698
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:31 → 69
      KN_motif; KN motif
      pfam12796
      Location:743 → 828
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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