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    ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704359, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARFGEF1provided by VGNC
    Official Full Name
    ADP ribosylation factor guanine nucleotide exchange factor 1provided by VGNC
    Primary source
    VGNC:VGNC:69834
    See related
    Ensembl:ENSMMUG00000014424
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARFGEF1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (67844110..67990670, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (65336695..65485376, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 5 Neighboring gene centrosome and spindle pole associated protein 1 Neighboring gene nucleophosmin pseudogene Neighboring gene uncharacterized LOC114680272 Neighboring gene uncharacterized LOC100427113 Neighboring gene carboxypeptidase A6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    brefeldin A-inhibited guanine nucleotide-exchange protein 1
    Names
    ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261046.1 → NP_001247975.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1

      See identical proteins and their annotated locations for NP_001247975.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045941
      UniProtKB/TrEMBL
      F7BID8, G7MZH5, I0FNI6
      Related
      ENSMMUP00000018947.4, ENSMMUT00000020241.4
      Conserved Domains (5) summary
      PLN03076
      Location:15 → 1766
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:698 → 882
      Sec7; Sec7 domain
      pfam09324
      Location:1220 → 1301
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:419 → 573
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:29 → 210
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      67844110..67990670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015145405.2 → XP_015000891.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X3

      UniProtKB/TrEMBL
      G7MZH5
      Conserved Domains (5) summary
      PLN03076
      Location:15 → 1760
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:698 → 882
      Sec7; Sec7 domain
      pfam09324
      Location:1220 → 1301
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:419 → 573
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:29 → 210
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    2. XM_015145403.2 → XP_015000889.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1

      UniProtKB/TrEMBL
      G7MZH5
      Conserved Domains (5) summary
      PLN03076
      Location:15 → 1766
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:698 → 882
      Sec7; Sec7 domain
      pfam09324
      Location:1220 → 1301
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:419 → 573
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:29 → 210
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    3. XM_015145404.2 → XP_015000890.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1

      UniProtKB/TrEMBL
      G7MZH5
      Conserved Domains (5) summary
      PLN03076
      Location:15 → 1766
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:698 → 882
      Sec7; Sec7 domain
      pfam09324
      Location:1220 → 1301
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:419 → 573
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:29 → 210
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    4. XM_015145407.2 → XP_015000893.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X4

      UniProtKB/TrEMBL
      G7MZH5
      Conserved Domains (5) summary
      COG5307
      Location:227 → 1333
      COG5307; Guanine-nucleotide exchange factor, contains Sec7 domain [General function prediction only]
      pfam01369
      Location:498 → 682
      Sec7; Sec7 domain
      pfam09324
      Location:1020 → 1101
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:219 → 373
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      cl09829
      Location:1433 → 1528
      Csy1_I-F; CRISPR/Cas system-associated protein Csy1

    5. XM_028852225.1 → XP_028708058.1  brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X2

      UniProtKB/TrEMBL
      G7MZH5
      Conserved Domains (1) summary
      PLN03076
      Location:4 → 1732
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
    Nucleotide Protein
    Heading Accession and Version

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