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    ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693362, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ERCC8provided by VGNC
    Official Full Name
    ERCC excision repair 8, CSA ubiquitin ligase complex subunitprovided by VGNC
    Primary source
    VGNC:VGNC:72425
    See related
    Ensembl:ENSMMUG00000021812
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ERCC8 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (59245323..59334665, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (58791808..58849143, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene ELOVL fatty acid elongase 7 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial pseudogene Neighboring gene guanine nucleotide-binding protein-like 3-like protein pseudogene Neighboring gene uncharacterized LOC114678794 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 2 Neighboring gene uncharacterized LOC114678795 Neighboring gene small integral membrane protein 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription-coupled nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4A-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nucleotide-excision repair complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA excision repair protein ERCC-8
    Names
    excision repair cross-complementing rodent repair deficiency, complementation group 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      59245323..59334665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849450.1 → XP_028705283.1  DNA excision repair protein ERCC-8 isoform X5

      Conserved Domains (2) summary
      sd00039
      Location:37 → 90
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:15 → 208
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_001082072.4 → XP_001082072.3  DNA excision repair protein ERCC-8 isoform X1

      UniProtKB/TrEMBL
      H9FPM0
      Related
      ENSMMUP00000028727.4, ENSMMUT00000030694.4
      Conserved Domains (2) summary
      sd00039
      Location:47 → 97
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:40 → 361
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_028849449.1 → XP_028705282.1  DNA excision repair protein ERCC-8 isoform X4

      UniProtKB/TrEMBL
      H9FPM0
      Conserved Domains (2) summary
      sd00039
      Location:36 → 75
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:31 → 295
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_028849447.1 → XP_028705280.1  DNA excision repair protein ERCC-8 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AB89, H9FPM0
      Related
      ENSMMUP00000075203.1, ENSMMUT00000105259.1
      Conserved Domains (2) summary
      sd00039
      Location:70 → 109
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:27 → 329
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_028849448.1 → XP_028705281.1  DNA excision repair protein ERCC-8 isoform X3

      UniProtKB/TrEMBL
      H9FPM0
      Conserved Domains (2) summary
      sd00039
      Location:56 → 95
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:13 → 315
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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