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    SLC12A6 solute carrier family 12 member 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697536, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLC12A6provided by VGNC
    Official Full Name
    solute carrier family 12 member 6provided by VGNC
    Primary source
    VGNC:VGNC:77389
    Locus tag
    EGK_17319
    See related
    Ensembl:ENSMMUG00000020935
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SLC12A6 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (10590080..10695468, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (10154035..10256126, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S8 pseudogene Neighboring gene katanin regulatory subunit B1 like 1 Neighboring gene ER membrane protein complex subunit 4 Neighboring gene NOP10 ribonucleoprotein Neighboring gene NUT midline carcinoma family member 1 Neighboring gene lysophosphatidylcholine acyltransferase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables potassium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 12 member 6
    Names
    solute carrier family 12 (potassium/chloride transporters), member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      10590080..10695468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141797.2 → XP_014997283.1  solute carrier family 12 member 6 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YR62, F6TMR9, G7MWK3, I0FI98
      Related
      ENSMMUP00000065912.1, ENSMMUT00000089796.1
      Conserved Domains (3) summary
      TIGR00930
      Location:109 → 1150
      2a30; K-Cl cotransporter
      pfam03522
      Location:774 → 1150
      SLC12; Solute carrier family 12
      cl00456
      Location:209 → 360
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_015141798.2 → XP_014997284.1  solute carrier family 12 member 6 isoform X2

      UniProtKB/TrEMBL
      F6TMR9, H9YWV0
      Related
      ENSMMUP00000068546.1, ENSMMUT00000097216.1
      Conserved Domains (3) summary
      TIGR00930
      Location:94 → 1135
      2a30; K-Cl cotransporter
      pfam03522
      Location:759 → 1135
      SLC12; Solute carrier family 12
      cl00456
      Location:194 → 345
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. XM_002804705.3 → XP_002804751.1  solute carrier family 12 member 6 isoform X3

      See identical proteins and their annotated locations for XP_002804751.1

      UniProtKB/TrEMBL
      F6VTM4, F7H2L1
      Related
      ENSMMUP00000077036.1, ENSMMUT00000079623.1
      Conserved Domains (3) summary
      TIGR00930
      Location:58 → 1099
      2a30; K-Cl cotransporter
      pfam03522
      Location:723 → 1099
      SLC12; Solute carrier family 12
      cl00456
      Location:158 → 309
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. XM_028850708.1 → XP_028706541.1  solute carrier family 12 member 6 isoform X4

      UniProtKB/TrEMBL
      F6TMR9
      Conserved Domains (1) summary
      TIGR00930
      Location:1 → 1011
      2a30; K-Cl cotransporter

    5. XM_015141799.2 → XP_014997285.1  solute carrier family 12 member 6 isoform X4

      UniProtKB/TrEMBL
      F6TMR9
      Related
      ENSMMUP00000027547.4, ENSMMUT00000029440.4
      Conserved Domains (1) summary
      TIGR00930
      Location:1 → 1011
      2a30; K-Cl cotransporter

    6. XM_028850709.1 → XP_028706542.1  solute carrier family 12 member 6 isoform X4

      UniProtKB/TrEMBL
      F6TMR9
      Related
      ENSMMUP00000033898.2, ENSMMUT00000040870.3
      Conserved Domains (1) summary
      TIGR00930
      Location:1 → 1011
      2a30; K-Cl cotransporter
    Nucleotide Protein
    Heading Accession and Version

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