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Conserved domains on  [gi|1622952295|ref|XP_028706542|]
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solute carrier family 12 member 6 isoform X4 [Macaca mulatta]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1011 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1320.10  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295    1 MDTRPKVSSLLSRMANYTNLTQGAKEHEEAENITEGKKKP-TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL 79
Cdd:TIGR00930   32 HDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIG 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   80 QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLvyivpr 159
Cdd:TIGR00930  112 LSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVL------ 185
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  160 aAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLG 239
Cdd:TIGR00930  186 -DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKGFFGLG 263
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  240 NRTlssrhidvcsktkesnnmtvpsklwgffcnssqffnvtcdeyFVHNNvtsIQGIPGLASGiitenlwgnylpkgeii 319
Cdd:TIGR00930  264 NEI------------------------------------------FSENF---IPGIPGPEGG----------------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  320 ekpsakssdvlgslnheyvlvdittsFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLF 399
Cdd:TIGR00930  282 --------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLF 335
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  400 GACIEGVVLRDKFGDAVK---------------------GNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQA 458
Cdd:TIGR00930  336 GACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQA 415
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  459 IAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRF 537
Cdd:TIGR00930  416 LCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRF 495
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  538 RYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWR 617
Cdd:TIGR00930  496 KYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWR 575
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  618 PQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLR 697
Cdd:TIGR00930  576 PQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLR 651
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  698 EGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNV------------- 764
Cdd:TIGR00930  652 EGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqeelendcse 730
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  765 -------------------------EQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKK 819
Cdd:TIGR00930  731 dsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKK 810
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  820 DLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLSKTERDREAqlvKDRnsmlrltsigsdedeet 899
Cdd:TIGR00930  811 DMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDP----------------- 865
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  900 etyqekvHMTWTKDKYMASrgqkaksmegfQDLlnmrpdQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 979
Cdd:TIGR00930  866 -------KMTWTKPWKITD-----------AEL------QSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPD 921
                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 1622952295  980 ENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1011
Cdd:TIGR00930  922 ELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1011 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1320.10  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295    1 MDTRPKVSSLLSRMANYTNLTQGAKEHEEAENITEGKKKP-TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL 79
Cdd:TIGR00930   32 HDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIG 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   80 QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLvyivpr 159
Cdd:TIGR00930  112 LSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVL------ 185
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  160 aAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLG 239
Cdd:TIGR00930  186 -DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKGFFGLG 263
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  240 NRTlssrhidvcsktkesnnmtvpsklwgffcnssqffnvtcdeyFVHNNvtsIQGIPGLASGiitenlwgnylpkgeii 319
Cdd:TIGR00930  264 NEI------------------------------------------FSENF---IPGIPGPEGG----------------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  320 ekpsakssdvlgslnheyvlvdittsFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLF 399
Cdd:TIGR00930  282 --------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLF 335
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  400 GACIEGVVLRDKFGDAVK---------------------GNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQA 458
Cdd:TIGR00930  336 GACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQA 415
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  459 IAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRF 537
Cdd:TIGR00930  416 LCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRF 495
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  538 RYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWR 617
Cdd:TIGR00930  496 KYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWR 575
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  618 PQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLR 697
Cdd:TIGR00930  576 PQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLR 651
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  698 EGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNV------------- 764
Cdd:TIGR00930  652 EGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqeelendcse 730
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  765 -------------------------EQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKK 819
Cdd:TIGR00930  731 dsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKK 810
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  820 DLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLSKTERDREAqlvKDRnsmlrltsigsdedeet 899
Cdd:TIGR00930  811 DMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDP----------------- 865
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  900 etyqekvHMTWTKDKYMASrgqkaksmegfQDLlnmrpdQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 979
Cdd:TIGR00930  866 -------KMTWTKPWKITD-----------AEL------QSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPD 921
                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 1622952295  980 ENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1011
Cdd:TIGR00930  922 ELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
51-621 2.08e-46

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 173.66  E-value: 2.08e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   51 GVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVpAGGSYFMISRALGPEFGGAVG 130
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  131 L--CFYLGTTFAAAmyiLGAIEIFLVYIVPRAAIfrsddalkesaamlNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 208
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDI--------------PYLWVWGAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  209 LACVIVSILAIYAGAI--KSSFAPPHFPVcmlgnrtlssrhidvcsktkesnnmtvpsklwgffcnssqffnvtcdEYFV 286
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIilLSGGNPNDGAI-----------------------------------------------FRYL 175
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  287 HNNVTSIQGIPGLASGIItenlwgnylpkgeiiekpsakssdvlgslnheYVLVdittsftllvgIFFPSVTGIMAGSNR 366
Cdd:pfam00324  176 GDNGGKNNFPPGFGKGFI--------------------------------SVFV-----------IAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  367 SGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG--VVLRDKFGDAVKGNLVVGTLSWPS--PWVIVIGSFFSTC 442
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndPGLLNDSASAASPFVIFFKFLGISglAPLINAVILTAAL 292
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  443 GAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHSKANGEPTWALLLTAAIAELGILIASLdlVAPILSMFFLMCYLFVNLAC 522
Cdd:pfam00324  293 SAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIV 368
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  523 ALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFA 602
Cdd:pfam00324  369 WGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLF 448
                          570
                   ....*....|....*....
gi 1622952295  603 LLRLEEGPPHTKNWRPQLL 621
Cdd:pfam00324  449 LIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
59-581 8.28e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 132.71  E-value: 8.28e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   59 NIFGVILFLRLTWVVGTAG--VLQAFAIVLICCcctMLTAISMSAIATNgvVP-AGGSYFMISRALGPEFGGAVGLCFYL 135
Cdd:COG0531     25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  136 GTTFAAAMYILGAIEiFLVYIVPRAAIFrsddalkesaamlnnmrVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVS 215
Cdd:COG0531    100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  216 ILAIYAgaikssfapphfpvcmlgnrtlssrhidvcsktkesnnmtvpsklWGFFcnssqffnvtcdeYFVHNNVTSIQG 295
Cdd:COG0531    162 LLLFIV---------------------------------------------VGLF-------------AFDPANFTPFLP 183
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  296 IPGLASGIitenlwgnylpkgeiiekpsakssdvlgslnheyvlvdittsFTLLVGIFFpSVTGIMAGSNRSGDLKDAQK 375
Cdd:COG0531    184 AGGGLSGV------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  376 SIPIGTILAILTTSFVYlsnvVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP--WVIVIGSFFSTCGAGLQSLTGAP 453
Cdd:COG0531    221 NIPRAIILSLLIVGVLY----ILVSLALTGVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  454 RLLQAIAKDNIIPflRVFGH-SKANGEPTWALLLTAAIAELGILI--ASLDLVAPILSMFFLMCYLFVNLAcALQTLLRT 530
Cdd:COG0531    297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRRR 373
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622952295  531 PNWRPRFRYYHWALSFMGMSICLALMFIS---SWYYAIVAMVIAGMIYKYIEYQ 581
Cdd:COG0531    374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1011 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1320.10  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295    1 MDTRPKVSSLLSRMANYTNLTQGAKEHEEAENITEGKKKP-TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL 79
Cdd:TIGR00930   32 HDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPpAGAVKFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIG 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   80 QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLvyivpr 159
Cdd:TIGR00930  112 LSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVL------ 185
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  160 aAIFRSDdALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLG 239
Cdd:TIGR00930  186 -DLLREN-GSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPAKGFFGLG 263
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  240 NRTlssrhidvcsktkesnnmtvpsklwgffcnssqffnvtcdeyFVHNNvtsIQGIPGLASGiitenlwgnylpkgeii 319
Cdd:TIGR00930  264 NEI------------------------------------------FSENF---IPGIPGPEGG----------------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  320 ekpsakssdvlgslnheyvlvdittsFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLF 399
Cdd:TIGR00930  282 --------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLF 335
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  400 GACIEGVVLRDKFGDAVK---------------------GNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQA 458
Cdd:TIGR00930  336 GACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQA 415
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  459 IAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRF 537
Cdd:TIGR00930  416 LCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRF 495
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  538 RYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWR 617
Cdd:TIGR00930  496 KYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWR 575
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  618 PQLLVLLKLDedlhVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLR 697
Cdd:TIGR00930  576 PQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLR 651
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  698 EGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEdARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNV------------- 764
Cdd:TIGR00930  652 EGVRHLIQASGLGRMKPNTLVMGYKKDWRQAE-PRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqvqeelendcse 730
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  765 -------------------------EQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKK 819
Cdd:TIGR00930  731 dsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKK 810
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  820 DLATFLYHLRIEAEVEVVEMhdsDISAytYERTLMMEQRSQMLRHMRLSKTERDREAqlvKDRnsmlrltsigsdedeet 899
Cdd:TIGR00930  811 DMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA---KDP----------------- 865
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  900 etyqekvHMTWTKDKYMASrgqkaksmegfQDLlnmrpdQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 979
Cdd:TIGR00930  866 -------KMTWTKPWKITD-----------AEL------QSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPD 921
                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 1622952295  980 ENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1011
Cdd:TIGR00930  922 ELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
51-621 2.08e-46

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 173.66  E-value: 2.08e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   51 GVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVpAGGSYFMISRALGPEFGGAVG 130
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  131 L--CFYLGTTFAAAmyiLGAIEIFLVYIVPRAAIfrsddalkesaamlNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 208
Cdd:pfam00324   80 WnyWLSWITVLALE---LTAASILIQFWELVPDI--------------PYLWVWGAVFLVLLTIINLVGVKWYGEAEFWF 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  209 LACVIVSILAIYAGAI--KSSFAPPHFPVcmlgnrtlssrhidvcsktkesnnmtvpsklwgffcnssqffnvtcdEYFV 286
Cdd:pfam00324  143 ALIKIIAIIGFIIVGIilLSGGNPNDGAI-----------------------------------------------FRYL 175
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  287 HNNVTSIQGIPGLASGIItenlwgnylpkgeiiekpsakssdvlgslnheYVLVdittsftllvgIFFPSVTGIMAGSNR 366
Cdd:pfam00324  176 GDNGGKNNFPPGFGKGFI--------------------------------SVFV-----------IAFFAFTGIELVGIA 212
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  367 SGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG--VVLRDKFGDAVKGNLVVGTLSWPS--PWVIVIGSFFSTC 442
Cdd:pfam00324  213 AGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndPGLLNDSASAASPFVIFFKFLGISglAPLINAVILTAAL 292
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  443 GAGLQSLTGAPRLLQAIAKDNIIPFlrVFGHSKANGEPTWALLLTAAIAELGILIASLdlVAPILSMFFLMCYLFVNLAC 522
Cdd:pfam00324  293 SAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIV 368
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  523 ALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFA 602
Cdd:pfam00324  369 WGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLF 448
                          570
                   ....*....|....*....
gi 1622952295  603 LLRLEEGPPHTKNWRPQLL 621
Cdd:pfam00324  449 LIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
59-581 8.28e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 132.71  E-value: 8.28e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295   59 NIFGVILFLRLTWVVGTAG--VLQAFAIVLICCcctMLTAISMSAIATNgvVP-AGGSYFMISRALGPEFGGAVGLCFYL 135
Cdd:COG0531     25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  136 GTTFAAAMYILGAIEiFLVYIVPRAAIFrsddalkesaamlnnmrVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVS 215
Cdd:COG0531    100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  216 ILAIYAgaikssfapphfpvcmlgnrtlssrhidvcsktkesnnmtvpsklWGFFcnssqffnvtcdeYFVHNNVTSIQG 295
Cdd:COG0531    162 LLLFIV---------------------------------------------VGLF-------------AFDPANFTPFLP 183
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  296 IPGLASGIitenlwgnylpkgeiiekpsakssdvlgslnheyvlvdittsFTLLVGIFFpSVTGIMAGSNRSGDLKDAQK 375
Cdd:COG0531    184 AGGGLSGV------------------------------------------LAALALAFF-AFTGFEAIANLAEEAKNPKR 220
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  376 SIPIGTILAILTTSFVYlsnvVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP--WVIVIGSFFSTCGAGLQSLTGAP 453
Cdd:COG0531    221 NIPRAIILSLLIVGVLY----ILVSLALTGVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGAS 296
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  454 RLLQAIAKDNIIPflRVFGH-SKANGEPTWALLLTAAIAELGILI--ASLDLVAPILSMFFLMCYLFVNLAcALQTLLRT 530
Cdd:COG0531    297 RLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRRR 373
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622952295  531 PNWRPRFRYYHWALSFMGMSICLALMFIS---SWYYAIVAMVIAGMIYKYIEYQ 581
Cdd:COG0531    374 PDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
635-1011 3.39e-31

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 127.35  E-value: 3.39e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  635 PRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQtiKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKH 714
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGRLSQKLRSELQKKA--YRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  715 NTVVMGWPNGWRQSE------------DA--------------------------------------------------- 731
Cdd:pfam03522   80 NILLMGYKSDWRTCDkeeleeyfnvihDAfdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  732 --RAWKTFIGTVRVTTAAHLALLV-------------------AKNISFFPSNVE--------QF----SEGNIDVWWIV 778
Cdd:pfam03522  160 nsKQDDDKSKLSKKDSNLSLSPDKstknpsgkdssksdklkkkSPSIILRTASNEkeilnnitQFqkkqKKGTIDVWWLY 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  779 HDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVemhdSDISAYTYERTLMMEQ 857
Cdd:pfam03522  240 DDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKETKKFFD 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  858 rsQMLRHMRLSKTERDREaqlvkdrnSMLRLTsigsdeDEETETYQEKVHmtwtkdkymasrgqkaksmegfqdlLNMRp 937
Cdd:pfam03522  316 --ELIEPFRLHEDDKEEE--------SAEKIT------DSELEALKEKTN-------------------------RQLR- 353
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622952295  938 dqsnvrrmhtavkLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1011
Cdd:pfam03522  354 -------------LRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
342-578 1.37e-13

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 74.27  E-value: 1.37e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  342 ITTSFTLLVGIFFpSVTGIMAGSNRSGDLKdaQKSIPIGTILAILTTSFVY-LSNVVLFGAC-IEGVVLRDKFGD---AV 416
Cdd:pfam13520  187 WPGVFAGFLGVLW-SFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYiLVNIAFFGVVpDDEIALSSGLGQvaaLL 263
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  417 KGNLVVGTLSWpspwVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGIL 496
Cdd:pfam13520  264 FQAVGGKWGAI----IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILSLILLL 339
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  497 IASLDLVAPI----LSMFFLMCYLFVNLACALqtLLRTPNWRPRFRYYHWALSFMGMsICLALMFISSWYYAIVAMVIAG 572
Cdd:pfam13520  340 LFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFLIVALFFPPVGPATGSS 416

                   ....*.
gi 1622952295  573 MIYKYI 578
Cdd:pfam13520  417 LNYAII 422
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
368-567 1.23e-04

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 45.89  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  368 GDLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPwvIVIGsfFSTCGAGL 446
Cdd:TIGR00911  259 EEVKNPYRTLPIAIIISMPIVTFIYvLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMP--ALVG--LSCFGSVN 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622952295  447 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANgEPTWALLLTAAIAELGILIASLDLVAPILSMFFlmcYLFVNLACALQT 526
Cdd:TIGR00911  335 GSLFSSSRLFFVGGREGHLPSLLSMIHVKRL-TPLPSLLIVCTLTLLMLFSGDIYSLINLISFAN---WLFNALAVAGLL 410
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1622952295  527 LLR--TPNWRPRFRyyhwalsfmgMSICLALMFISSWYYAIVA 567
Cdd:TIGR00911  411 WLRykRPEMNRPIK----------VPLFFPVFFLLSCLFLIIL 443
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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