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    ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704407, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARFGEF2provided by VGNC
    Official Full Name
    ADP ribosylation factor guanine nucleotide exchange factor 2provided by VGNC
    Primary source
    VGNC:VGNC:69836
    See related
    Ensembl:ENSMMUG00000019635
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARFGEF2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (84124494..84238552)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (15415122..15528756, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC714617 Neighboring gene phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Neighboring gene uncharacterized LOC114670499 Neighboring gene chromosome segregation 1 like Neighboring gene staufen double-stranded RNA binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    brefeldin A-inhibited guanine nucleotide-exchange protein 2
    Names
    ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      84124494..84238552
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148796.2 → XP_015004282.1  brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8J8XHI2, F7AUW7, G7N4L1, H9EN13
      Related
      ENSMMUP00000025793.3, ENSMMUT00000027578.4
      Conserved Domains (5) summary
      PLN03076
      Location:11 → 1711
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:643 → 827
      Sec7; Sec7 domain
      pfam09324
      Location:1167 → 1248
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:370 → 524
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:28 → 198
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    2. XM_015148797.2 → XP_015004283.1  brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XHI2, G7N4L1, H9EN13
      Conserved Domains (5) summary
      PLN03076
      Location:11 → 1710
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
      pfam01369
      Location:642 → 826
      Sec7; Sec7 domain
      pfam09324
      Location:1166 → 1247
      DUF1981; Domain of unknown function (DUF1981)
      pfam12783
      Location:369 → 523
      Sec7_N; Guanine nucleotide exchange factor in Golgi transport N-terminal
      pfam16213
      Location:28 → 198
      DCB; Dimerization and cyclophilin-binding domain of Mon2

    3. XM_028828499.1 → XP_028684332.1  brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8J8XHI2, G7N4L1, H9EN13
      Conserved Domains (1) summary
      PLN03076
      Location:11 → 1687
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
    Nucleotide Protein
    Heading Accession and Version

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